Xue, Yuan; Park, Han Seul; Jiang, Chao; Yu, Jin-Quan published the artcile< Palladium-Catalyzed β-C(sp3)-H Nitrooxylation of Ketones and Amides Using Practical Oxidants>, Quality Control of 112-63-0, the main research area is ketone amide nitrooxylation palladium catalyst carbon hydrogen bond activation.
Herein, a Pd(II)-catalyzed β-C(sp3)-H nitrooxylation of ketones and native amides was reported. The fine-tuned removable aminooxyamide auxiliary enabled β-C(sp3)-H functionalization of various aliphatic ketones. Practical iron(III) nitrate nonahydrate was used as the nitrate source and a single-electron oxidant for Pd(II)/Pd(III)/Pd(IV) catalysis. For amide substrates, N-iodosuccinimide (NIS) was applied as a bystanding two-electron oxidant in combination with silver nitrate for β-C(sp3)-H nitrooxylation. Palladacycle intermediates were isolated and characterized to elucidate the reaction mechanism for the C(sp3)-H activation of ketones with the L,X-type imino-amide directing group.
ACS Catalysis published new progress about Amides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics