Ushio, Kazutoshi; Nakagawa, Kouzou; Nakagawa, Katsuhiko; Watanabe, Kunio published the artcile< An easy access to optically pure (R)-malic acid via enantioselective hydrolysis of diethyl malate by Rhizopus lipase>, Quality Control of 617-55-0, the main research area is malate enzymic resolution lipase; malic acid optically active.
(±)-Di-Et malate was enantioselectively hydrolyzed by crude Rhizopus lipase (Saiken) to leave optically pure (≥99% enantiomeric excess) (R)-(+)-malic acid in 20% recovery. The combination of di-Pr malate and lipase AY (Amano) also gave the (R)-enantiomer with an enantiomeric excess of ≥95% and about 20% recovery in a short reaction time.
Biotechnology Letters published new progress about Enzymic resolution. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Quality Control of 617-55-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics