Lee, Sun Bu; Park, Jin Hyun; Bae, Han Yong published the artcile< Hydrophobic Amplification Enabled High-Turnover Phosphazene Superbase Catalysis>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is beta arylated sulfido sulfonyl fluoride chemoselective preparation; organic synthesis; organocatalysis; phosphazenes; thia-Michael addition; water chemistry.
Herein a significant “”on-water”” hydrophobic amplification was achieved, enabling a high-turnover catalytic thia-Michael addition to produce unprecedented β-arylated-β-sulfido sulfonyl fluorides. Amounts as low as 100 ppm (0.01 mol %) of the phosphazene superbase were sufficient to successfully catalyzed the reaction with excellent chemo-/site-selectivity and with optimal functional group tolerance. Several β-arylated ethene sulfonyl fluorides were converted into thia-Michael adducts up to >99% yields. The mild conditions, high turnover, neutral pH, and scalability of the sustainable catalytic process benefit the preparation of potential pharmaceuticals (e.g., polyisoprenylated methylated protein Me esterase inhibitors) and organic materials (e. g., electrolyte additives).
ChemSusChem published new progress about Catalysis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics