Kobbelgaard, Sara; Brandes, Sebastian; Jorgensen, Karl Anker published the artcile< Asymmetric organocatalyzed [1,3]-sigmatropic rearrangements>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is beta amino acid asym preparation organocatalysis; sigmatropic rearrangement beta hydroxy ester cinchona alkaloid catalyst.
The first organocatalyzed enantioselective [1,3]-sigmatropic O- to N-rearrangement reactions are presented. The reactions take place under regio- and enantioselective control, and are catalyzed by cinchona alkaloids. Two reactions have been developed; the first one is the rearrangement of imidates to amides, while the other rearrangement occurs from carbamates to amines via a decarboxylation. Both transformations give nitrogen protected β-amino acid derivatives as the product. These novel asym. organocatalyzed [1,3]-sigmatropic O- to N-rearrangement reactions provide a reliable and efficient synthetic method for obtaining enantio-enriched β-amino acid derivatives in good yields from racemic starting materials.
Chemistry – A European Journal published new progress about [1,3]-Sigmatropic rearrangement (asym., O- to N-rearrangement reaction). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics