Cui, Hai-Lei; Huang, Ji-Rong; Lei, Jie; Wang, Zhao-Feng; Chen, Shi; Wu, Li; Chen, Ying-Chun published the artcile< Direct Asymmetric Allylic Alkylation of Butenolides with Morita-Baylis-Hillman Carbonates>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is Morita Baylis Hillman carbonate butenolide regioselective asym allylic alkylation; cinchona alkaloid catalyst asym allylic alkylation; substituted butenolide stereoselective preparation; bicyclic lactone preparation.
The direct asym. allylic alkylation of β,γ-butenolides with MBH carbonates to access γ,γ-disubstituted butenolides containing adjacent quaternary and tertiary chiral centers, e.g. I, has been presented in excellent stereoselectivities (86-96% ee, dr >95:5) and moderate to good yield (50-83%). Their synthetic utility has been well demonstrated by the facile construction of bicyclic lactones bearing 4-5 stereogenic centers, e.g. II.
Organic Letters published new progress about Allylic alkylation catalysts, stereoselective. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics