Riley, Malcolm; Perham, Richard N. published the artcile< Reaction of protein amino groups with methyl 5-iodopyridine-2-carboximidate. Possible general method of preparing isomorphous heavy-atom derivatives of proteins>, Related Products of 112-63-0, the main research area is iodopicolinimidate protein derivative; picolinimidate iodo insulin derivative; pyridinecarboximidate iodo insulin derivative.
The title carboximidate (I), prepared in 4 steps from 5-iodopicolinic acid, reacted specifically with the NH2 groups of oxidized insulin under mild conditions giving N-monosubstituted amidines. Modification of lysine residues inhibited tryptic cleavage at such residues. I reacts specifically with the aromatic NH2 groups of 3-amino-L-tyrosine at pH 5.0 giving a 2-arylbenzoxazole.
Biochemical Journal published new progress about Peptides Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics