Lv, Daqi; Sun, Qiao; Zhou, Huan; Ge, Liang; Qu, Yanjie; Li, Taian; Ma, Xiaoxu; Li, Yajun; Bao, Hongli published the artcile< Iron-Catalyzed Radical Asymmetric Aminoazidation and Diazidation of Styrenes>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is azidoarylethyl benzenesulfonimide diazidoarylalkane enantioselective preparation; iron dioxazolinyldibenzofuran catalyst enantioselective aminoazidation diazidation aryl alkene; radical reaction mechanism iron catalyzed aminoazidation diazidation aryl alkene; aminoazidation; asymmetric catalysis; iron catalysis; radical group transfer.
Asym. aminoazidation and diazidation of alkenes are straightforward strategies to build value-added chiral nitrogen-containing compounds from feedstock chems. They provide direct access to chiral organoazides and complement enantioselective diamination. Despite the advances in non-asym. reactions, asym. aminoazidation or diazidation based on acyclic systems has not been previously reported. Here we describe the iron-catalyzed intermol. asym. aminoazidation and diazidation of styrenes. The method is practically useful and requires relatively low loading of catalyst and chiral ligand. With mild reaction conditions, the reaction can be completed on a 20 mmol scale. Studies of the mechanism suggest that the reaction proceeds via a radical pathway and involves stereocontrol of an acyclic free radical which probably takes place through a group transfer mechanism.
Angewandte Chemie, International Edition published new progress about Alkyl azides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (benzylic). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics