Aparna, P.; Kothari, Seema; Banerji, Kalyan K. published the artcile< Kinetics and mechanism of oxidation of hydroxy acids by pyridinium hydrobromide perbromide>, Application In Synthesis of 112-63-0, the main research area is oxidation hydroxy acid pyridinium hydrobromide perbromide.
The oxidation of glycolic, lactic, mandelic and malic acids by pyridinium hydrobromide perbromide (PHPB) in acetic acid-water mixture (3:7, volume/volume) gives oxo acids. The reaction is first-order each in PHPB and the hydroxy acid. Addition of pyridinium hydrobromide does not affect the rate, indicating that PHPB itself is the reactive oxidizing species. The oxidation of α-deuteriomandelic acid shows the presence of a primary kinetic isotope effect (kH/kD = 5.07). The reaction does not exhibit a solvent isotope effect [k(H2O)/k(D2O) = 1.01]. The rate decreases with an increase in acetic acid content in the solvent mixture A mechanism involving hydride ion transfer to the oxidant is proposed.
Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry published new progress about Isotope effect. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics