Month: October 2022

Ohanessian, Jacqueline; Caron, Michel published the artcile< A spectrophotometric study of the carbohydrate binding site of peanut lectin>, Application In Synthesis of 112-63-0, the main research area is peanut lectin carbohydrate binding; structure activity carbohydrate binding lectin.

The difference spectra spectrophotometric method (spectra recorded between 260 and 300 nm, determined at 10°) was used to determine the binding constants for specific binding of sugars (16 mono-and oligosaccharides) to peanut lectin. For C(6), an extracyclic chain is needed for lectin interaction, and orientation of the -OH group on C(6) is essential; substitution of the hydroxymethyl group decreases the strength of the association A free axial -OH on C(4) is needed for binding. A C(2) equatorial hydroxyl group is not essential for interaction, but the axial position of this group decreases the binding. Methylation of C(1) favors association; there seems to be a slight preference for the α-anomer configuration. For the glycosidic bonds, compounds with the β(1→4) linkage bind more strongly to the lectin than those with the α(1→6) linkage. Overall, these results show that the sequence C(4)-O(4), C(5), C(6)-O(6) of the galactopyranosyl ring is involved in the interactions in the carbohydrate binding site of peanut lectin as postulated previously (Lotan, R., et al, 1975), and that for di- and oligosaccharides, it appears that the configuration of C(1), the nature of the osidic bond and of the 2nd residue may influence the strength of the association

Lectins: Biology, Biochemistry, Clinical Biochemistry published new progress about Agglutinins and Lectins Role: BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Guo, Tao; Ding, Yalan; Zhou, Lili; Xu, Haiyan; Loh, Teck-Peng; Wu, Xiaojin published the artcile< Palladium-Catalyzed anti-Michael Reductive Heck Reaction of α,β-Unsaturated Esters>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is palladium catalyzed anti Michael reductive Heck unsaturated ester.

A general intermol. anti-Michael reductive Heck reaction of α,β-unsaturated esters with organobromides has been developed. Most topical classes of aryl, heteroaryl, and vinyl bromides were found to efficiently react with a variety of internal conjugated alkenes. This protocol set up a platform toward diverse α-arylated 1,6-dicarbonyl frameworks found in natural products and drugs, which are still highly challenging targets in traditional α-arylation protocols because of competitive selectivity of enolation. A removable directing group, gram-scale reaction, and modification of complex mols. have addnl. demonstrated that the anti-Michael reductive Heck reaction is a powerful complementary strategy to the classical α-arylation approaches. Preliminary mechanistic studies are consistent with our proposed mechanistic design.

ACS Catalysis published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hor, Papan Kumar; Goswami, Debabrata; Ghosh, Kuntal; Tako, Miklos; Halder, Suman Kumar; Mondal, Keshab Chandra published the artcile< Preparation of rice fermented food using root of Asparagus racemosus as herbal starter and assessment of its nutrient profile>, HPLC of Formula: 112-63-0, the main research area is rice fermented food Asparagus root herbal starter nutrient profile.

The popularity of traditional fermented food products is based on their healthiness. The addition of a starter brings consistent, desirable, and predictable food changes with improved nutritive, functional, and sensory qualities. The addition of a mixture of plant residues as a starter or source of microbes is an age-old practice to prepare traditional fermented food and beverages, and most of the reported data on traditional foods were based on the anal. of the final product. The contribution of an individual starter component (plant residue) is not exptl. substantiated for any traditional fermented food, but this data are very essential for the formulation of an effective starter. In this study, Asparagus racemosus, which used as a common ingredient of starter for preparation of rice fermented food in the Indian sub-continent, was used as a starter for the preparation of rice fermented food under laboratory scale, and its microbial and nutrient profile was evaluated. The fermented product was a good source of lactic acid bacteria, Bifidobacterium sp., yeast, etc. The food product was acidic and enriched with lactic acid and acetic acid with titratable acidity of 0.65%. The content of protein, fat, minerals, and vitamins (water-soluble) was considerably improved. Most notably, oligosaccharide (G3-matotriose), unsaturated fatty acids (ω3, ω6, ω7, and ω9), and a pool of essential and non-essential amino acids were enriched in the newly formulated food. Thus, the herbal starter-based rice fermented food would provide important macro- and micronutrients. They could also deliver large numbers of active microorganisms for the sustainability of health. Therefore, the selected plant part conferred its suitability as an effective starter for the preparation of healthier rice-based food products.

Systems Microbiology and Biomanufacturing published new progress about Batch fermentation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ignatiuk, Zaneta A.; Janicki, Mikolaj J.; Gora, Robert W.; Konieczny, Krzysztof; Kowalczyk, Rafal published the artcile< Applications of Thermal Activation, Ball-milling and Aqueous Medium in Stereoselective Michael Addition of Nitromethane to En-ynones Catalyzed by Chiral Squaramides>, HPLC of Formula: 112-63-0, the main research area is nitromethane enynone chiral squaramide enantioselective regioselective Michael addition; nitromethyl aryl phenyl pentynone.

Stereoselective addition of nitromethane to conjugated en-ynones was performed through the application of chiral squaramides. Three non-classical approaches to promote the addition reaction were tested, including activation of the nucleophile by inorganic base in a biphasic aqueous system, thermal activation, and ball-milling. Hydrogen-bonding catalysis was effective in all these methods, providing 1,4-addition products in high yields and stereoselectivities of up to 98% requiring 1-5 mol% of Cinchona alkaloid squaramide.

Advanced Synthesis & Catalysis published new progress about Alcohols, propargyl Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hu, Shaojian; Zhu, Jianhua; Wu, Bencheng; Ma, Rui; Li, Xiaohui published the artcile< Green synthesis of ester base oil with high viscosity - Part II: Reaction kinetics study>, Electric Literature of 112-63-0, the main research area is ester base oil high viscosity green synthesis reaction kinetics.

As an eco-friendly lubricant base oil, ester base oil is receiving increasing attention. However, studies on synthetic reaction kinetics of high viscosity complex ester have been rarely reported. In this work, based on the principle of equal reactivity of all functional groups and simplified kinetics models, synthetic reaction kinetics for high viscosity complex ester was investigated in two steps. As for the esterification of trimethylolpropane with glutaric acid, the activation energies of the first and second stage were 55.3 and 73.5 kJ/mol, resp. As for the esterification of the first step products with 2-ethylhexanoic acid, the activation energies of the first and second stage were 60.6 and 98.2 kJ/mol, resp. As for the esterification of the first step products with n-heptanoic acid, its activation energy was 68.9 kJ/mol. A mutation phenomenon on reaction order from zero to second order was discovered, which could be explained by the strong adsorption of organic acid on catalyst surface. The conversion rate of carboxyl of synthetic reaction for mixed acid ester was estimated by simulation, and average relative error was less than 3.0%. The synthetic process of high viscosity complex ester was considered to consist of a series of parallel-consecutive reactions with addition-elimination mechanism.

Chemical Engineering Research and Design published new progress about Activation energy. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Huiting; Li, Jiuyan; Liu, Di; Huang, Tingting; Li, Deli published the artcile< Effects of Electron Affinity and Steric Hindrance of the Trifluoromethyl Group on the π-Bridge in Designing Blue Thermally Activated Delayed Fluorescence Emitters>, Application of C19H34O2, the main research area is OLED TADF electron affinity steric hindrance; electron affinity steric hindrance trifluoromethyl pi Bridge; triazine acceptor carbazole tertbutylcarbazole donor; TADF; blue emission; electron affinity; fluorescence; steric hindrance.

To explore the correlation of the acceptor electron affinity and the mol. conformation to the thermally activated delayed fluorescence (TADF) feature, a series of D-π-A mols. were designed and synthesized with triazine (Trz) as the acceptor (A) and carbazole (Cz) or tert-butylcarbazole (BuCz) as the donor (D). On the phenylene bridge between D and A, Me or trifluoromethyl was incorporated close either to D or to A to tune the mol. conformation and the electron-withdrawing ability of acceptor. Both the twist angles and the singlet and triplet energy difference (ΔEST) were observed strongly dependent on the type and position of the substituent on the π-bridge. Only those mols. with trifluoromethyl locating close to the D side, namely TrzCz-CF3 and TrzBuCz-CF3, exhibit TADF feature, verifying that both sufficient electron affinity of the A unit and large dihedral angle between D and the π-bridge are necessary to ensure the occurrence of TADF. The blue organic light-emitting diodes OLED fabricated with TrzCz-CF3 and TrzBuCz-CF3 achieved external quantum efficiencies of 9.40% and 14.22% with CIE coordinates of (0.19, 0.23) and (0.18, 0.29) resp. This study provides practical design strategy for blue TADF materials particularly when planar and less crowded group is used as donor.

Chemistry – A European Journal published new progress about Blue-emitting electroluminescent devices. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yasuno, Takumi; Ohe, Tomoyuki; Kataoka, Hiroki; Hashimoto, Kosho; Ishikawa, Yumiko; Furukawa, Keigo; Tateishi, Yasuhiro; Kobayashi, Toi; Takahashi, Kyoko; Nakamura, Shigeo; Mashino, Tadahiko published the artcile< Fullerene derivatives as dual inhibitors of HIV-1 reverse transcriptase and protease>, Electric Literature of 623-50-7 , the main research area is pyridinium fullerene preparation dual inhibitor HIV reverse transcriptase protease; piperidinium fullerene preparation dual inhibitor HIV reverse transcriptase protease; proline fullerene preparation dual inhibitor HIV reverse transcriptase protease; Fullerene; HIV protease; HIV reverse transcriptase.

In the present study, we newly synthesized three types of novel fullerene derivatives: pyridinium-type derivatives, piperidinium-type derivatives, and proline-type derivatives Among the assessed compounds, some were found to inhibit both HIV reverse transcriptase and HIV protease (HIV-PR), with IC50 values in the low micromolar range being observed Regarding HIV-PR inhibition activity, proline-type derivatives, bearing an alkyl chain between the hydroxylmethylcarbonyl (HMC) moiety and pyrrolidine ring, were more potent than other derivatives This result might indicate that connecting HMC moieties with proline-type fullerene derivatives through properly sized alkyl chain leads to improved HIV-PR inhibitory activity.

Bioorganic & Medicinal Chemistry Letters published new progress about AIDS (disease). 623-50-7 belongs to class esters-buliding-blocks, and the molecular formula is C4H8O3, Electric Literature of 623-50-7 .

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Kui; Wang, Meng-Meng; Dou, Hong-Xi; Xing, Si-Yang; Zhu, Bo-Lin; Cui, Jian-Hua published the artcile< Comparative Study on the Supramolecular Assemblies Formed by Calixpyridinium and Two Alginates with Different Viscosities>, Related Products of 112-63-0, the main research area is alginate calixpyridinium viscosity aggregation.

In this work, a comparative study on the supramol. assemblies formed by calixpyridinium and two alginates with different viscosities was performed. We found that sodium alginate (SA) with medium viscosity (SA-M) had a better capability to induce aggregation of calixpyridinium in comparison with SA with low viscosity (SA-L) because of the stronger electrostatic interactions between calixpyridinium and SA-M. Therefore, the morphol. of calixpyridinium-SA-M supramol. aggregates was a compact spherical structure, while that of calixpyridinium-SA-L supramol. aggregates was an incompact lamellar structure. As a result, adding much more amount of 1,3,6,8-pyrenetetrasulfonic acid tetrasodium salt to calixpyridinium-SA-M solution was required to achieve the balance of the competitive binding, and in comparison with calixpyridinium-SA-L supramol. aggregates, calixpyridinium-SA-M supramol. aggregates were more sensitive to alkali. However, for the same reason, in comparison with calixpyridinium-SA-M supramol. aggregates, calixpyridinium-SA-L supramol. aggregates were much more stable in water not only at room temperature but also at a higher temperature, and even in salt solution Therefore, in comparison with calixpyridinium-SA-L supramol. aggregates, calixpyridinium-SA-M supramol. aggregates exhibited a completely opposite response to acid because of the generation of salt. Because SA is an important biomaterial with excellent biocompatibility, it is anticipated that this comparative study is extremely important in constructing functional supramol. biomaterials.

ACS Omega published new progress about Acidity. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xin, Qingping; Zhao, Meixue; Guo, Jianping; Huang, Dandan; Zeng, Yinan; Zhao, Yuhang; Zhang, Teng; Zhang, Lei; Wang, Shaofei; Zhang, Yuzhong published the artcile< Light-responsive metal-organic framework sheets constructed smart membranes with tunable transport channels for efficient gas separation>, Application of C19H34O2, the main research area is light metal organic framework sheet membrane gas separation.

Exploring a new type of smart membrane with tunable separation performance is a promising area of research. In this study, new light-responsive metal-organic framework [Co(azpy)] sheets were prepared by a facile microwave method for the first time, and were then incorporated into a polymer matrix to fabricate smart mixed matrix membranes (MMMs) applied for flue gas desulfurization and decarburization. The smart MMMs exhibited significantly elevated SO2(CO2)/N2 selectivity by 184(166)% in comparison with an unfilled polymer membrane. The light-responsive characteristic of the smart MMMs was investigated, and the permeability and selectivity of the Co(azpy) sheets-loaded smart MMMs were able to respond to external light stimuli. In particular, the selectivity of the smart MMM at the Co(azpy) content of 20% for the SO2/N2 system could be switched between 341 and 211 in situ irradiated with Vis and UV light, while the SO2 permeability switched between 58 Barrer and 36 Barrer, resp. This switching influence was mainly ascribed to the increased SO2 adsorption capacity in the visible light condition, as verified by adsorption test. The CO2 permeability and CO2/N2 selectivity of MMMs in the humidified state could achieve 248 Barrer and 103.2, surpassing the Robeson′s upper bound reported in 2019.

RSC Advances published new progress about Adsorption. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shi, Yang; Pan, Bo-Wen; Li, Wen-Chao; Wang, Qing; Wu, Qiong; Pan, Meng; Fu, Hong-Zheng published the artcile< Synthesis and biological evaluation of Isosteviol derivatives as FXa inhibitors>, HPLC of Formula: 19241-24-8, the main research area is isosteviol derivative preparation FXa inhibitor anticoagulant; FXa inhibitors; Isosteviol; Structural modification.

Firstly, a series of Isosteviol derivatives were synthesized and evaluated for FXa inhibitory activity. Among these compounds, the inhibitory activity of three compounds on FXa was better than that of Isosteviol. Secondly, surface plasmon resonance (SPR) assays were performed for selected compounds The three compounds have similar kinetic signatures, and affinity values were at μM level. Thirdly, two compounds displayed moderate-to-high anticoagulation activity and showed similar sensitivity to PT and aPTT. These findings will provide new insight into the exploration of FXa inhibition.

Bioorganic & Medicinal Chemistry Letters published new progress about Anticoagulants. 19241-24-8 belongs to class esters-buliding-blocks, and the molecular formula is C11H13NS, HPLC of Formula: 19241-24-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics