Month: October 2022

Yang, Yiwei; Kong, Mengya; Feng, Pengfei; Meng, Ruiqian; Wei, Xiaohe; Su, Pingru; Cao, Jing; Feng, Wei; Liu, Weisheng; Tang, Yu published the artcile< Self-Assembly of Heterogeneous Structured Rare-Earth Nanocrystals Controlled by Selective Crystal Etching and Growth for Optical Encoding>, Recommanded Product: Ethyl 3-oxo-3-phenylpropanoate, the main research area is self assembly rare earth nanocrystal etching optical encoding.

Programmatically assembling inorganic nanocrystals (NCs) into long-range-ordered superstructures has been well-documented as a theme to construct novel materials with unique properties. Herein, one-dimensional oriented self-assembly of core-shell structured rare-earth doped β-NaREF4 NCs is reported. In the epitaxial growth process, β-NaREF4 crystals featuring larger neg. lattice mismatch usually exhibited longitudinal growth preference. In this case, the lateral crystal of the hexagonal prisms would be etched by OA- ions along the direction parallel to the (001) facets. This anisotropic morphol. evolution can lead to the anisotropic noncovalent interactions between long-chain alkyls of oleic acid mols. and contribute to the oriented self-assembly in the 〈001〉 direction. On the basis of the studies on the heterogeneous NC self-assembly, a rare-earth nanohybrid assembly is further prepared by functionalizing the NC surface with a pH-responsive ligand N-(2-pyridinyl)benzoylacetamide (HPBA), and this nanohybrid self-assembly exhibits great potential in spatial-temporal dimensional optical encoding. This study provides a novel strategy based on selective crystal etching and epitaxial growth for oriented self-assembly of NCs and represents an important step toward the design of well-defined superstructures with unique properties.

ACS Applied Nano Materials published new progress about Coded information. 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Recommanded Product: Ethyl 3-oxo-3-phenylpropanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhao, Wenbo; Yun, Keming published the artcile< Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is Glioblastoma; Propofol; Temozolomide; Tumor-associated macrophages.

Temozolomide (TMZ) is the first-line drug for the clin. treatment of glioblastoma (GBM), but drug resistance limits its treatment benefits. This study was intended to investigate whether propofol could restrict the resistance of GBM cells to TMZ and uncover the underlying mechanisms. Human GBM cell line U251 and TMZ-resistant U251/TMZ cell line were transplanted into mice to construct GBM and TMZ-resistant GBM xenograft tumors. Tumor growth in mice was monitored, and the tumor tissues were collected for biochem. anal. THP-1 cell differentiated into M0 subtype macrophage using phorbol 12-myristate 13-acetate (PMA). The culture medium of M0 macrophage was collected for treating U251 cells with the presence or absence of propofol or propofol + DMOG (HIF-1α activator). Results showed that propofol significantly enhanced the inhibitory effect of TMZ on tumor growth, macrophage infiltration and inflammation in TMZ-resistant GBM xenograft tumors in vivo. Compared with GBM xenograft tumors, higher expression of HIF-1α, O6-methylguanine-DNA methyltransferase (MGMT), p-p65 and cyclooxygenase 2 (Cox2) was observed in TMZ-resistant GBM xenograft tumors, but propofol co-treatment markedly reduced the expression of these proteins. In in vitro experiments, culture medium from M0 macrophage promoted U251 cell survival, inflammation and expression of HIF-1α, MGMT, p65 and Cox2, whereas inhibited cell apoptosis. However, propofol suppressed the PMA-induced THP-1 M0 macrophage activation, and propofol-treated culture medium from M0 macrophage blocked all the effects of M0 medium on U251 cells. Addnl., DMOG reversed the effect of propofol-treated M0 medium on U251 cells. In conclusion, Propofol restricted TMZ resistance via inhibiting macrophage activation and down-regulating HIF-1α expression in GBM.

Experimental Cell Research published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xu, Li; Wang, Han; Yu, Qian-qian; Ge, Jin-ru; Zhang, Xian-zheng; Mei, Dan; Liang, Fa-qin; Cai, Xiao-yu; Zhu, Yue; Shu, Jin-ling; Tai, Yu; Wei, Wei; Zhang, Ling-ling published the artcile< The monomer derivative of paeoniflorin inhibits macrophage pyroptosis via regulating TLR4/ NLRP3/ GSDMD signaling pathway in adjuvant arthritis rats>, Synthetic Route of 112-63-0, the main research area is paeoniflorin macrophage pyroptosis TLR NLRP GSDMD signaling pathway arthritis; Adjuvant arthritis; Macrophage pyroptosis; Monomer derivative of paeoniflorin; Rheumatoid arthritis; TLR4/NLRP3/GSDMD signaling pathway.

This study was aimed to investigate the effect of monomer derivative of paeoniflorin (MDP) on macrophage pyroptosis mediated by TLR4/NLRP3/GSDMD signaling pathway in adjuvant arthritis (AA) rats. Wistar rats were divided into normal group, AA model group, MDP (50 mg/kg) group and MTX (0.5 mg/kg) group. The expression of TLR4, NLRP3 and GSDMD in macrophage were detected by immunofluorescence assay. The expression of TLR4 and the ratio of macrophage pyroptosis were analyzed by flow cytometry. Cell morphol. was observed by SEM. The cytokine levels of IL-18 and IL-1β were detected by ELISA. The expressions of proteins related to macrophage pyroptosis were detected by western blot. MDP has a therapeutic effect on rats AA by reducing the secondary inflammation and improving pathol. changes. The results of X-ray imaging and ultrasound images showed that MDP could inhibit bone erosion, soft tissue swelling, and joint space narrowing. Macrophage pyroptosis was found in secondary inflammation of AA rats. The expressions of TLR4, MyD88, NLRP3, Caspase-1, ASC, and GSDMD-N in macrophage were increased, the levels of IL-18 and IL-1β were enhanced, and the morphol. of pyroptosis could be observed MDP could inhibit macrophage polarization and macrophage pyroptosis, and down-regulated the cytokine levels of IL-18 and IL-1β in AA rats. MDP could regulate the M1/m2 ratio, decreased the ratio of macrophage pyroptosis and down-regulated the expressions of TLR4, MyD88, NLRP3, Caspase-1, ASC, and GSDMD-N in vivo and in vitro. Abnormal activation of TLR4/NLRP3/GSDMD signaling pathway may be involved in macrophage pyroptosis in AA rats. The therapeutic effect of MDP on AA rats is related to the inhibition of macrophage pyroptosis by regulating the TLR4/NLRP3/GSDMD signaling pathway.

International Immunopharmacology published new progress about Arthritis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ma, Jin-ling; Zhang, Wen-chao; Wang, Xiao-dong; Tang, Ming; Huang, Zheng-yong; Li, Jian; Zhang, Han; Yang, Xiao-hui; Guo, Zai-ping; Wang, Yu published the artcile< Revealing the mechanism of saturated ether electrolyte for improving the long-cycling stability of Na-O2 batteries>, HPLC of Formula: 112-63-0, the main research area is sodium oxygen battery saturated ether electrolyte stability revealing mechanism.

Na-O2 batteries have been considered as promising energy storage systems due to their high energy d. and low cost. Their poor cycle life, however, and their unclear interfacial formation mechanisms have greatly hindered the development of Na-O2 batteries. In this work, compared to the commonly used ether-based electrolyte (0.5 M sodium trifluomethanesulfonate in tetraethylene glycol di-Me ether), its saturated electrolyte is employed for Na-O2 batteries to achieve around four times longer cycle life. Both experiments and simulations suggest that the enhanced cycling stability could be attributed to the use of saturated electrolyte, which plays important roles in reducing the dissolution of NaO2, thereby easing the shuttle effect of O2-; sharply decreasing dissolved oxygen, thus eliminating Na anode oxidation; and effectively suppressing Na dendrite growth because of the high Na+ flux in saturated electrolyte, thus relieving the nonuniformity of the Na+ flux.

Nano Energy published new progress about Absorption. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Santi, D.; Triyono; Morin, J. V. published the artcile< The preparation of Merbau wood waste ash-based catalyst and its utilization for biodiesel production from low-grade palm oil>, SDS of cas: 112-63-0, the main research area is Merbau wood waste ash catalyst palm oil biodiesel production.

The Merbau wood waste ash-based catalyst was prepared via various calcination temperatures and was applied for biodiesel production from low-grade palm oil. The thermal investigations of calcination of Merbau wood were carried out at temperatures of 500, 600, 700, 800, and 900°C for 3 h. It was led to M700 as a catalyst based on the highest basicity as confirmed by the basicity test and x-ray diffraction anal. The M700 mass toward methanol volume ratio was performed at 5%, 10%, 15%, 20% (w/v) on the application of conversion of LGPO into biodiesel. The products of biodiesel were prepared via reflux at temperature 80°C for 2 h and were characterized by GC-MS. The biodiesel product is predominantly Me palmitate. The ash-methanol ratio of 15% gives the optimum biodiesel fraction conversion (78.7% weight/weight). The optimum selectivity of the yield total of biodiesel given by 10%, namely 48.9% weight/weight, resulted in Me ester (biodiesel) with C15-C19 consisting of Me myristate, Me palmitate, Me linoleate, Me oleic, Me stearate. Moreover, a 10% weight catalyst to methanol showed the optimum decrease of FFA (89.0 ± 0.6%).

Rasayan Journal of Chemistry published new progress about Basicity. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Parida, Chandrakanta; Maity, Rajendra; Chandra Sahoo, Subas; Chandra Pan, Subhas published the artcile< α-Nitro-α,β-Unsaturated Ketones: An Electrophilic Acyl Transfer Reagent in Catalytic Asymmetric Friedel-Crafts and Michael Reactions>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is nitroethylnaphthyl ester enantioselective preparation; nitroethyl substituted enol ester enantioselective preparation; squaramide catalyst enantioselective tandem Friedel Crafts acyl transfer reaction; nitroenone acyl transfer reagent enantioselective reaction naphthol phenol.

In the presence of a tert-leucine-derived squaramide and mol. sieves, 2-naphthols and electron-rich phenols underwent tandem enantioselective Friedel-Crafts and acyl transfer reactions with α-nitro-α,β-unsaturated ketones such as I (R = Ph, 4-i-PrC6H4, 4-PhOC6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-PhC6H4, 3-BrC6H4, 2,4-Me2C6H3, 2-naphthyl, cyclohexyl, i-Pr; R1 = Ph, 4-MeC6H4, 4-MeOC6H4, 4-ClC6H4, 4-BrC6H4, 4-O2NC6H4, 3-ClC6H4, 3-F3CC6H4, 2-FC6H4, 2-ClC6H4, 2-Br-4-MeC6H3, 2-furyl) to yield nitroethylnaphthol ester such as II (R = Ph, 4-i-PrC6H4, 4-PhOC6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-PhC6H4, 3-BrC6H4, 2,4-Me2C6H3, 2-naphthyl, cyclohexyl, i-Pr; R1 = Ph, 4-MeC6H4, 4-MeOC6H4, 4-ClC6H4, 4-BrC6H4, 4-O2NC6H4, 3-ClC6H4, 3-F3CC6H4, 2-FC6H4, 2-ClC6H4, 2-Br-4-MeC6H3, 2-furyl). Dimedone and a pyrazolone underwent tandem enantioselective Michael and acyl transfer reactions with I (R = R1 = Ph) to yield nitroethyl-substituted enol esters. Further reactions of II (R = R1 = Ph) are disclosed.

Organic Letters published new progress about Alkenes, nitro Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (α-acyl). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Rui-Qi; Huang, Tao; Gong, Shu-Ling published the artcile< Preparation of high hydroxyl self-emulsifying polyester and compounding with acrylate>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is hydroxyl polyester acrylate emulsion film waterborne coating.

Waterborne saturated polyester (WSP) with high hydroxyl content was prepared through solution polymerization by using stepwise feeding and stage heating methods. The stability of polyester dispersion was enhanced via control of the mol. structure and polymerization process. The effect of polymerization conditions, monomer types, and catalyst types was determined The effects of the alc.-to-acid ratio, trimethylolpropane content, the feeding method, the content of terminal monomer and branching monomer on the dispersion were investigated. The stability of the self-emulsifying polyester and water resistance of the film were excellent. The transesterification of WSP afforded waterborne unsaturated polyester. Polyester-acrylate composite emulsion was prepared by phys. blending or copolymerization with unsaturated polyester. The viscosity of the composite emulsion, hardness and water resistance were improved. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 48278.

Journal of Applied Polymer Science published new progress about Acid number. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Phukan, Kandarpa; Chutia, Gobinda Prasad; Chutia, Sudipta published the artcile< Synthesis of Biodiesel from Indigenous Xanthium Strumarium (Cocklebur) Non-Edible Oil Available in Assam, India>, Electric Literature of 112-63-0, the main research area is Xanthium strumarium biodesel synthesis transesterification.

Xanthium strumarium seed oils had been investigated as a potential non-edible biodiesel feedstock. The Xanthium strumarium seeds expressed about 38% oil content via solvent extracton technique. Physicochem. parameters of oil such as acid value, iodine value, saponification value, etc. were determined exptl. to prove its feasibility for biodiesel production The Xanthium strumarium Me esters or biodiesel were synthesized via transesterification reaction using K2CO3 as a catalyst and a 97% yield was attained at optimum reaction parameters. The characterization of produced biodiesel was done by fourier transform IR (FTIR), proton NMR (1H NMR) and carbon-13 NMR (13C NMR) spectroscopy. Gas chromatog.-mass spectrometry (GC-MS) anal. was employed to determine the composition of fatty acid Me esters of methylated oil. The fuel parameters like d., viscosity, acid value, calorific value, flash point, pour and cloud point of the biodiesel were evaluated as per American Society for Testing and Materials (ASTM) D6751 standard

ChemistrySelect published new progress about Acid number. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Shan-Jun; Cui, Hai-Lei; Jiang, Kun; Li, Rui; Ding, Zhen-Yu; Chen, Ying-Chun published the artcile< Enantioselective Allylic Amination of Morita-Baylis-Hillman Carbonates Catalysed by Modified Cinchona Alkaloids>, COA of Formula: C19H34O2, the main research area is ester unsaturated imido asym synthesis; carbonate ester unsaturated enantioselective allylic amination cyclic imide cinchona.

An efficient procedure for the asym. allylic amination of Morita-Baylis-Hillman carbonates I (R = Ph, 2-ClC6H4, 3-MeC6H4, 1-naphthyl, 2-thienyl, etc.) with cyclic imides II (phthalimide, tetrachlorophthalimide, tetrabromophthalimide, cis-hexahydrophthalimide, 1,8-naphthalimide) catalyzed by com. available cinchona alkaloids is reported. It proves to be a facile protocol that affords α-methylene-β-imido esters III with good-to-excellent enantioselectivities (up to 94 % ee) and in high yields (up to 97 %). (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009).

European Journal of Organic Chemistry published new progress about Allylic substitution reaction (stereoselective). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mondal, Biswarup; Rangaiah, Gade Pandu; Jana, Amiya K. published the artcile< Optimizing algal biodiesel production from a novel reactive distillation based unit: Reducing CO2 emission and cost>, Electric Literature of 112-63-0, the main research area is carbon dioxide emission algal biodiesel.

The algal biodiesel as a potential alternative to conventional petroleum fuel and first-generation biofuel has been explored extensively but the efficacy of its production in a reactive distillation (RD) unit is yet to be analyzed thoroughly. In this contribution, the performance of the RD column is enhanced by process intensification and optimization. A multi-objective optimization (MOO) strategy is framed for optimizing the RD column for three conflicting objectives. For this MOO, the elitist non-dominated sorting genetic algorithm (NSGA-II) is employed. From the obtained Pareto-optimal front, one optimal solution for RD design is selected using the technique for order of preference by similarity to ideal solution (TOPSIS) with entropy information for weighting of objectives. To further reduce the environmental impact and optimal usage of internal energy, a novel thermally coupled reactive distillation (TCRD) column is suggested. Finally, a biodiesel production unit is developed by integrating a decanter with the TCRD column, to produce biodiesel product of 99.45 weight% purity. Performance of the TCRD column is better than the conventional RD column, in terms of CO2 emission reduction (14.49%) and total annual cost savings (3.72%). Energetic sustainability of the proposed biodiesel process is determined by net energy ratio (NER) of 1.79, net energy value (NEV) of 18.2 and net renewable energy value (NREV) of 41.4 MJ/kg.

Chemical Engineering and Processing published new progress about Biodiesel fuel. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics