Month: October 2022

Baratta, Walter; Barbato, Cinzia; Magnolia, Santo; Siega, Katia; Rigo, Pierluigi published the artcile< Chiral and Nonchiral [OsX2(diphosphane)(diamine)] (X: Cl, OCH2CF3) Complexes for Fast Hydrogenation of Carbonyl Compounds>, HPLC of Formula: 112-63-0, the main research area is osmium phosphino ferrocene diamine diphosphine complex preparation hydrogenation catalyst; ketone hydrogenation osmium phosphino ferrocene diamine diphosphine complex catalyst; aldehyde hydrogenation osmium phosphino ferrocene diamine diphosphine complex catalyst; enantioselective hydrogenation catalyst osmium diamine diphosphine complex.

The osmium complexes trans-[OsCl2(dppf)(diamine)] (dppf: 1,1′-bis(diphenylphosphino)ferrocene; diamine: ethylenediamine in 3, 1,3-propylenediamine in 4) were prepared by the reaction of [OsCl2(PPh3)3] (1) with the ferrocenyl diphosphine dppf and the corresponding diamine in dichloromethane. The reaction of derivative 3 with NaOCH2CF3 in toluene afforded the alkoxide cis-[Os(OCH2CF3)2(dppf)(ethylenediamine)] (5). The novel precursor [Os2Cl4(P(m-tolyl)3)5] (2) gave the chiral complexes trans-[OsCl2(diphosphine)(1,2-diamine)] (6-9; diphosphine: (R)-[6,6′-dimethoxy(1,1′-biphenyl)-2,2′-diyl]bis[1,1-bis(3,5-dimethylphenyl)phosphine] (xylMeObiphep) or (R)-(1,1′-binaphthalene)-2,2′-diylbis[1,1-bis(3,5-dimethylphenyl)phosphine] (xylbinap); diamine = (R,R)-1,2-diphenylethylenediamine (dpen) or (R,R)-1,2-diaminocyclohexane (dach)), obtained by the treatment of 2 with the diphosphine and the 1,2-diamine in toluene at reflux temperature Compounds 3-5 in ethanol and in the presence of NaOEt catalyze the reduction of Me aryl, dialkyl, and diaryl ketones and aldehydes with H2 at low pressure (5 atm), with substrate/catalyst (S/C) ratios of 10,000-200,000 and achieving turnover frequencies (TOFs) of up to 3.0 × 105 h-1 at 70°. By employment of the chiral compounds 6-9, different ketones, including alkyl aryl, bulky tert-Bu, and cyclic ketones, have successfully been hydrogenated with enantioselectivities up to 99% and with S/C ratios of 5000-100,000 and TOFs of up to 4.1 × 104 h-1 at 60°.

Chemistry – A European Journal published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lotierzo, Andrea; Meaney, Shane P.; Bon, Stefan A. F. published the artcile< Effect of the addition of salt to Pickering emulsion polymerizations using polymeric nanogels as stabilizers>, SDS of cas: 3290-92-4, the main research area is polystyrene preparation sodium chloride nanogel pickering emulsion polymerization stabilizer.

Nanogels made from crosslinked block copolymer micelles are used as stabilizers in the Pickering emulsion polymerization of styrene. The effect of the addition of salt, i.e. NaCl, on the emulsion polymerization is studied. It is shown that an increase in ionic strength of the dispersing medium in these polymerizations led to the formation of latexes of larger diameters Along with an increase in size, the morphol. of these polymer colloids changed from Janus to patchy with an increase in number of nanogels adsorbed on the polymer surface, as a function of the salt concentration in water. In particular, at the highest tested ionic strength, ca. 25 mM, fully armored polymeric particles surrounded by a dense layer of adsorbed stabilizing nanogels were formed. Kinetic studies carried out at varying NaCl concentrations suggested that particle formation in the reaction followed a combination of a coagulative nucleation mechanism, characterized by a clustering process of Janus precursors to form bigger aggregates, and droplet nucleation. Preliminary film formation studies on latexes made with Bu acrylate as a comonomer indicated the potential of this technique for the production of coherent polymer films which included a substructure of functional nanogels.

Polymer Chemistry published new progress about Crosslinking. 3290-92-4 belongs to class esters-buliding-blocks, and the molecular formula is C18H26O6, SDS of cas: 3290-92-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Aitbelale, Rachid; Achak, Mounia; Chhiti, Younes; Munoz Rujas, Natalia; Aguilar, Fernando; M’hamdi Alaoui, Fatima Ezzahrae published the artcile< Effects of 2-Butanol Addition on Waste Cooking Oil Biodiesel Density: An Updated Experimental Measurement and Thermodynamic Modeling Study>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is butanol cooking oil biodiesel mixture density thermodn modeling EOS.

Biodiesels will become the most popular alternative energy resource to fossil diesels; they can be used alone or blended with an oxygenated additive in any proportion. The properties of biodiesels strongly depend on the type of the fatty acid Me esters (FAME) that compose them. The main objective of the present work is to study the influence of 2-butanol addition on the waste cooking oil biodiesel (WCOB), for this fact, the new exptl. d. data (952 points) of WCOB + 2-butanol binary mixtures over a wide range [seven compositions; 0 ≤ (WCOB) mole fraction x ≤ 1] between 0.1 and 140 MPa and 298.15 and 393.15 K are presented. The exptl. data were correlated using Tait and perturbed chain-statistical associating fluid theory (PC-SAFT) equations of state (EoS), to the knowledge, this is the 1st time that d. measurements for the WCOB + 2-butanol mixture are correlated using the famous PC-SAFT EoS. The Tait equation predicts successfully the d. with a global absolute average deviation (AAD) of 0.089%, while the PC-SAFT model correlates well the d. with a very small global AAD of 0.223% in each composition Also, contrary to the Tait equation, the PC-SAFT model can explain some interactions between fluid mols. From the exptl. data, the excess volumes VE were calculated and fitted using the Redlich-Kister equation with a very small global standard deviation of 7.49 × 10-5 cm3/mol, and VE show a pos. and sym. parabolic shape in all composition ranges. Finally, the isobaric thermal expansivity, αp, and the isothermal compressibility, κT, were derived from the Tait equation and their observed trend was as expected.

Journal of Chemical & Engineering Data published new progress about Binary mixtures. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ko, Youngmin; Kim, Hong-I.; Cho, Sung-Ju; Lee, Kyung Min; Jung, Gwan Yeong; Park, Hyeokjun; Park, Se Hwan; Lee, Yun Jung; Bae, Youngjoon; Lee, Young-Ro; Kim, Kyoungoh; Kwak, Sang Kyu; Lee, Sang-Young; Kang, Kisuk published the artcile< Liquid-Based Janus Electrolyte for Sustainable Redox Mediation in Lithium-Oxygen Batteries>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is liquid Janus electrolyte sustainable redox mediation lithium oxygen battery.

The discovery of a reliable electrolyte system remains one of the key challenges for the development of advanced lithium-oxygen batteries. To date, no single electrolyte is verified to be stable and compatible with both the cathode (e.g., oxygen radicals, lithium peroxide, etc.) and anode (lithium metal) for lithium-oxygen batteries. In this work, a novel liquid-based Janus electrolyte system consisting of two different immiscible liquid phases is proposed and it is demonstrated that this system is remarkably effective in promoting the sustainable operation of redox-mediated lithium-oxygen batteries. The liquid-based Janus electrolyte is rationally designed by considering its compatibility with the lithium-oxygen cell environment, the solubility difference of target soluble species, and the mutual immiscibility of the two liquid phases. By combining spectral characterization, a phase-separation experiment, and in situ observation of the electrochem. cell, it is revealed that the liquid-based Janus electrolyte suppresses the migration of redox mediators from one liquid phase to the other, thereby preventing the detrimental shuttle effect. The enhanced stability of redox mediation leads to improved cycling performance of the cell. The various combinations possible for the liquid-based Janus electrolyte open a new unexplored pathway for the design of advanced electrolyte systems for lithium-oxygen batteries.

Advanced Energy Materials published new progress about Batteries (lithium-oxygen batteries). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xu, Jihong; Wu, Pei-Jung; Lai, Tzung-Huei; Sharma, Pratibha; Canella, Alessandro; Welker, Alessandra M.; Beattie, Christine E.; Elder, J. Brad; Easley, Michelle; Lonser, Russell; Jacob, Naduparambil K.; Pietrzak, Maciej; Timmers, Cynthia M.; Lang, Frederick; Sampath, Deepa; Puduvalli, Vinay K. published the artcile< Disruption of DNA repair and survival pathways through heat shock protein inhibition by onalespib to sensitize malignant gliomas to chemoradiation therapy>, COA of Formula: C19H34O2, the main research area is glioma hemoradiation therapy DNA repair survival heat shock protein.

Proficient DNA repair by homologous recombination (HR) facilitates resistance to chemoradiation in glioma stem cells (GSC). We evaluated whether compromising HR by targeting HSP90, a mol. chaperone required for the function of key HR proteins, using onalespib, a long-acting, brain-penetrant HSP90 inhibitor, would sensitize high-grade gliomas to chemoradiation in vitro and in vivo. The ability of onalespib to deplete HR client proteins, impair HR repair capacity, and sensitize glioblastoma (GBM) to chemoradiation was evaluated in vitro in GSCs, and in vivo using zebrafish and mouse intracranial glioma xenograft models. The effects of HSP90 inhibition on the transcriptome and cytoplasmic proteins was assessed in GSCs and in ex vivo organotypic human glioma slice cultures. Treatment with onalespib depleted CHK1 and RAD51, two key proteins of the HR pathway, and attenuated HR repair, sensitizing GSCs to the combination of radiation and temozolomide (TMZ). HSP90 inhibition reprogrammed the transcriptome of GSCs and broadly altered expression of cytoplasmic proteins including known and novel client proteins relevant to GSCs. The combination of onalespib with radiation and TMZ extended survival in a zebrafish and a mouse xenograft model of GBM compared with the standard of care (radiation and TMZ) or onalespib with radiation. The results of this study demonstrate that targeting HR by HSP90 inhibition sensitizes GSCs to radiation and chemotherapy and extends survival in zebrafish and mouse intracranial models of GBM. These results provide a preclin. rationale for assessment of HSP90 inhibitors in combination with chemoradiation in patients with GBM.

Clinical Cancer Research published new progress about Animal gene Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (ATM). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Brzek, Pawel; Roussel, Damien; Konarzewski, Marek published the artcile< Mice selected for a high basal metabolic rate evolved larger guts but not more efficient mitochondria>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is micer basal metabolic rate gut efficient mitochondria; artificial selection; basal metabolic rate; endothermy; laboratory mice; mitochondria; mitochondrial efficiency.

Intra-specific variation in both the basal metabolic rate (BMR) and mitochondrial efficiency (the amount of ATP produced per unit of oxygen consumed) has profound evolutionary and ecol. consequences. However, the functional mechanisms responsible for this variation are not fully understood. Mitochondrial efficiency is neg. correlated with BMR at the interspecific level but it is pos. correlated with performance capacity at the intra-specific level. This discrepancy is surprising, as theories explaining the evolution of endothermy assume a pos. correlation between BMR and performance capacity. Here, we quantified mitochondrial oxidative phosphorylation activity and efficiency in two lines of laboratory mice divergently selected for either high (H-BMR) or low (L-BMR) levels of BMR. H-BMR mice had larger livers and kidneys (organs that are important predictors of BMR). H-BMR mice also showed higher oxidative phosphorylation activity in liver mitochondria but this difference can be hypothesized to be a direct effect of selection only if the heritability of this trait is low. However, mitochondrial efficiency in all studied organs did not differ between the two lines. We conclude that the rapid evolution of BMR can reflect changes in organ size rather than mitochondrial properties, and does not need to be accompanied obligatorily by changes in mitochondrial efficiency.

Proceedings of the Royal Society B: Biological Sciences published new progress about Animal organ, lymphoid. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wen, Jie; Jia, Zhanyu; Zhang, Xiaopeng; Pan, Mingwang; Yuan, Jinfeng; Zhu, Lei published the artcile< Tough, thermo-responsive, biodegradable and fast self-healing polyurethane hydrogel based on microdomain-closed dynamic bonds design>, Application of C19H34O2, the main research area is self healing polyurethane hydrogel mech property.

Self-healing versatile polyurethane (PU) hydrogel is a class of appealing material, which is by reason of its broadening application prospects such as in tissue engineering, drug delivery, and sense technol. fields. However, it is still a huge challenge to combine superior mech. robustness, thermo-responsiveness, biodegradability with self-healing capability for PU hydrogels. Herein, we fabricated a novel multifunctional PU hydrogel with fast self-healing and excellent mech. performance, largely depending on a microdomain-closed design because of the dynamic disulfide bonds embedded in hard segments as well as principally being closed in viscoelastic hard segments microdomain. Besides, PCL in soft segments provided good biodegradability, the mech. performance, self-healing capability, and biodegradability of PU hydrogels could be modulated by altering the chain extender 4-aminophenyl disulfide APDS addition amount The obtained optimal PU hydrogels showed sensitive thermo-responsiveness, rapid mech. recovery (10 min), high mech. strength (tensile stress of 3.3 MPa), superior stretching toughness (strain of 1055%), and outstanding self-healing ability (self-healing efficiency of 97%). The strategy described here provides a promising avenue to design and fabricate intelligent and multifunctional PU hydrogels.

Materials Today Communications published new progress about Complex modulus, tan δ. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Si, Anshupriya; Misra, Anup Kumar published the artcile< Facile synthesis of a rare sugar intermediate: D-gulopyranosyl cyanide>, Synthetic Route of 4098-06-0, the main research area is glycoside nitrile gulopyranosyl cyanide glycosylation preparation hydroxylation.

Convenient synthesis of D-gulopyranosyl cyanide has been achieved in high yield using a two step reaction sequence from D-galactal derivative The reaction condition is simple and suitable for scaling up. A bi-metallic reagent system consisting of CeCl3.7H2O and RuCl3.H2O has been used for the NaIO4 mediated cis-dihydroxylation of sugar olefin derivative i.e. pseudo-glycal.

Trends in Carbohydrate Research published new progress about Cyanation. 4098-06-0 belongs to class esters-buliding-blocks, and the molecular formula is C12H16O7, Synthetic Route of 4098-06-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Miki, Akinori; Nishikawa, Kei; Kamesui, Go; Matsushima, Hisayoshi; Ueda, Mkito; Rosso, Michel published the artcile< In situ interferometry study of ionic mass transfer phenomenon during the electrodeposition and dissolution of Li metal in solvate ionic liquids>, Application In Synthesis of 112-63-0, the main research area is interferometry ionic mass transfer electrodeposition dissolution lithium ionic liquid.

A digital holog. microscope was used to observe the Li+ concentration profile in situ, accompanied by the electrodeposition and electrochem. dissolution of Li metal in a solvate ionic liquid The concentration profile showed a linear relation with the square root of time in a quasi-two-dimensional electrochem. cell that could restrict natural convection fluid motion. For the anodic reaction, the electrochem. dissolution of Li metal induced an increase in concentration in the vicinity of the anode surface. Solvate ionic liquids have an enormous Li salt concentration, and the concentration increase induces a drastic increase in the viscosity of the electrolyte, resulting in a change in cell voltage. In situ Raman spectroscopy supported the development of the concentration profile near the electrode surface. The coordination of the chem. species also changed with the development of concentration profile induced by electrodeposition and electrochem. dissolution of Li metal in the solvate ionic liquid This study emphasizes that the development of a concentration profile is more important for a concentrated electrolyte (e.g., solvated ionic liquid) than a conventional 1 M class battery electrolyte. This is because the concentration in the vicinity of the electrode can deviate from the ideal molar ratio of Li salt and solvents due to the electrochem. reaction.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about Battery electrolytes. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lin, Songnian; Fang, Kan; Hashimoto, Masaru; Nakanishi, Koji; Ojima, Iwao published the artcile< Design and synthesis of a novel photoaffinity taxoid as a potential probe for the study of paclitaxel-microtubules interactions>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is taxoid photoaffinity label preparation paclitaxel microtubule.

A novel and non-radioactive bifunctional photoaffinity probe (BPP) for the study of paclitaxel-microtubules interactions is designed and synthesized. This new BPP-taxoid bears a 3-nitro-5-trifluoromethyl-diazirinyl-phenoxyacetyl group at C-3’N for photoaffinity/photocleavage and a biotin subunit at C-7 for affinity chromatog.

Tetrahedron Letters published new progress about Microtubule. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics