Chalyk, Bohdan A.; Isakov, Andrei A.; Butko, Maryna V.; Hrebeniuk, Kateryna V.; Savych, Olena V.; Kucher, Olexandr V.; Gavrilenko, Konstantin S.; Druzhenko, Tetiana V.; Yarmolchuk, Vladimir S.; Zozulya, Sergey; Mykhailiuk, Pavel K. published the artcile< Synthesis of 6-Azaspiro[4.3]alkanes: Innovative Scaffolds for Drug Discovery>, COA of Formula: C19H34O2, the main research area is azaspiroalkane preparation; alkene benzylazomethine ylide cycloaddition.
New scaffolds for drug discovery, 6-azaspiro[4.3]alkanes, I (R = H, F; A = O, S, SO2, etc.; EWG = COOEt, CN, NO2, etc.) have been synthesized in two steps from four-membered-ring ketones: cyclobutanone, thienone, N-Boc-azetidinone (Boc = tert-butoxycarbonyl), etc. The key transformation was the reaction between electron-deficient exocyclic alkenes and an in-situ generated N-benzylazomethine ylide.
European Journal of Organic Chemistry published new progress about [3+2] Cycloaddition reaction. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics