Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. 87-13-8, formula is C10H16O5, Name is Diethyl 2-(ethoxymethylene)malonate. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Recommanded Product: Diethyl 2-(ethoxymethylene)malonate.
Mohamed, Mosselhi A. M.;Abdel-Hafez, Shams H.;Gobouri, Adil A. research published 《 Nucleosides 11: synthesis of new derivatives of pyrido[2,3-d]pyrimidines and their nucleosides》, the research content is summarized as follows. Reaction of 6-amino-2-methylthio-3-methyluracil with Et ethoxymethyleneoxaloacetate or methyl(Z)-2-acetylamino-3-dimethylaminopropenoates afforded di-Et 2-(1,6-dihydro-1-methyl-2-(methylthio)-6-oxo-pyrimidin-4-yl-amino)methylene malonate or (2E)-Me 3-(1,6-dihydro-1-methyl-2-(methylthio)-6-oxo-pyrimidin-4-yl-amino)-2-acetamidoacrylate, resp. Cyclization of each of the latter products by sodium ethoxide afforded new pyrido[2,3-d]pyrimidines, which were ribosylated with 1-O-acetyl-2,3,5-O-benzoyl-β-D-ribofuranose by the silylation method yielded the protected nucleosides. The protected nucleosides were debenzoylated by sodium methoxide to afford novel pyrido[2,3-d]pyrimidine nucleosides, e.g. I (R = CO2Et, NHAc). The structural assignments for the new compounds were based on their elemental anal. and spectroscopic data.
Recommanded Product: Diethyl 2-(ethoxymethylene)malonate, Diethyl ethoxymethylenemalonate is a useful research compound. Its molecular formula is C10H16O5 and its molecular weight is 216.23 g/mol. The purity is usually 95%.
Diethyl ethoxymethylidenemalonate is a matrix effect reagent used in analytical chemistry. It is often used as a substrate for the cycloaddition process, which produces malondialdehyde and hydrochloric acid. The UV-absorption of the malondialdehyde can be measured to determine the concentration of the sample. Diethyl ethoxymethylidenemalonate is also used as a dna template in binding constants, where it binds with amines to form complexes that are then analyzed by light emission. It has been shown to have an inhibitory effect on gyrase and trifluoroacetic acid, both enzymes involved in DNA replication., 87-13-8.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics