Zhu, Sheng; Lin, Wen-qing; Zhang, Xiao-mei published the artcile< Process improvement on the synthesis of (S)-(+)-3-hydroxytetrahydrofuran>, SDS of cas: 617-55-0, the main research area is process improvement synthesis hydroxy THF preparation; tetrahydrofuranol preparation asym synthesis.
A method for the synthesis of the title compound [i.e., (S)-(+)-3-hydroxytetrahydrofuran] is reported here. Said target compound (overall yield 43.2%, 99.0% enantiomeric excess) was prepared by a synthetic sequence involving the esterification of L-malic acid, reduction and cyclization through intramol. dehydration. The product structure was determined by NMR.
Hecheng Huaxue published new progress about Cyclization. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, SDS of cas: 617-55-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics