Baddeley, Kate L.; Cook, Matthew J. published the artcile< A highly selective Bi(OTf)3 mediated fragmentation-contraction of é?ortholactones. A facile route to functionalized ç»?lactones>, SDS of cas: 4098-06-0, the main research area is lactone preparation pyranyl ortholactone fragmentation acetate migration ring contraction.
A very selective method for the formation of ç»?lactones from pyranyl ortholactones has been developed which occurs via a fragmentation-acetate migration-ring contraction process. The reaction is very functional group tolerant, providing functionalized ç»?lactones as a single isomeric product following the ring contraction. Mechanistic studies indicate the reaction is mediated by triflic acid liberated from Bi(OTf)3 in a slow and controlled manner providing excellent chemo and regioselectivity. We propose the triflic acid acts as both a proton and a nucleophile source with triflate anion mediating the fragmentation process.
Tetrahedron published new progress about Fragmentation reaction. 4098-06-0 belongs to class esters-buliding-blocks, and the molecular formula is C12H16O7, SDS of cas: 4098-06-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics