《Copper-Catalyzed C-H Fluorination/Functionalization Sequence Enabling Benzylic C-H Cross Coupling with Diverse Nucleophiles》 was published in Organic Letters in 2020. These research results belong to Vasilopoulos, Aristidis; Golden, Dung L.; Buss, Joshua A.; Stahl, Shannon S.. Category: esters-buliding-blocks The article mentions the following:
Alkylbenzenes underwent regioselective fluorination with N-fluorobenzenesulfonimide in the presence of CuOAc and bathophenanthroline mediated by methylboronic acid and lithium carbonate in chlorobenzene to yield secondary and tertiary benzylic fluorides. The benzylic fluorides generated in these reactions were reactive electrophiles in the presence of the hydrogen-bond donor hexafluoroisopropanol or the Lewis acid BF3·Et2O, yielding benzylic ethers, alcs., protected amines, and diarylalkanes directly from the alkylarenes. The experimental process involved the reaction of tert-Butyl carbamate(cas: 4248-19-5Category: esters-buliding-blocks)
tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. Halogenation, in which one or more hydrogen atoms of an amine is replaced by a halogen atom, occurs with chlorine, bromine, and iodine, as well as with some other reagents, notably hypochlorous acid (HClO). With primary amines the reaction proceeds in two stages, producing N-chloro- and N,N-dichloro-amines, RNHCl and RNCl2, respectively. With tertiary amines, an alkyl group may be displaced by a halogen.Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics