Van de Poel, Herve; Guillaumet, Gerald; Viaud-Massuard, Marie-Claude published the artcile< Synthesis of 6,7,8,9-tetrahydropyrido[2,3-b]indolizine and 3,4-dihydro-2H-pyrido[2',3':4,5]pyrrolo[2,1-b][1,3]oxazine derivatives as new melatonin receptor ligands>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is tricyclic azaindolic hormone melatonin hydropyridoindolizine hydropyridopyrrolooxazine synthesis; melatonin receptor ligand tetrahydropyridoindolizine dihydropyridopyrrolooxazine synthesis; bromopropyloxopyrrolopyridine intramol homolytic cyclization hydropyridoindolizine hydropyridopyrrolooxazine synthesis; hydropyridoindolizine hydropyridopyrrolooxazine synthesis melatonin receptor ligand intramol homolytic cyclization.
The synthesis of new tricyclic azaindolic analogs of the hormone melatonin is described. Treatment of 1-(4-bromobutyl)pyrrolo[3,2-b]pyridine derivative with tributyltin hydride and AIBN results in radical cyclisation to give the 6,7,8,9-tetrahydropyrido[2,3-b]indolizine ring system. A new synthetic approach of pyridopyrrolo[2,1-b][1,3]oxazine moiety is shown to be accomplished readily from 1-(3-bromopropyl)-2-oxopyrrolopyridine derivative with sodium hydride in N,N-dimethylformamide.
Tetrahedron Letters published new progress about Radical cyclization. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics