Pistelli, Luisa; Benassi, Sandra; Migliore, Lucia; Papa, Stefania; Andreassi, Maria Grazia published the artcile< Synthesis and biological activity of a series of isoindolone derivatives related to cytochalasins>, Reference of 112-63-0, the main research area is isoindolone derivative preparation lymphocyte binucleation cytostatic; cytochalasin analog preparation lymphocyte binucleation cytostatic.
A series of hydrogenated isoindolone derivatives structurally related to cytochalasin B has been synthesized and their ability to induce binucleation in the human lymphocytes were tested. All compounds were found able to inhibit cell cytokinesis at different extent in the range (3.12-25 μmol/L) respect to the neg. control; however the highest percentage of binucleated cells is induced by Cytochalasin B.
Farmaco published new progress about Cytokinesis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics