Luo, Zhenli; Wan, Shanhong; Pan, Yixiao; Yao, Zhen; Zhang, Xin; Li, Bohan; Li, Jiajie; Xu, Lijin; Fan, Qing-Hua published the artcile< Metal-Free Reductive Amination of Ketones with Amines Using Formic Acid as the Reductant under BF3 · Et2O Catalysis>, Synthetic Route of 94-02-0, the main research area is ketone amine formic acid boron trifluoride etherate reductive amination; alkylamine preparation.
BF3·Et2O was found to effectively catalyze reductive amination of ketones with amines employing formic acid as the reductant under metal-free conditions. This transformation tolerated a broad range of primary and secondary amines and differently decorated ketones, delivering N-alkylated amines in good to excellent yields with high compatibility of functional groups. The synthetic potential of this protocol was demonstrated by its application in the preparation of biol. and pharmaceutically relevant compounds
Asian Journal of Organic Chemistry published new progress about Amines Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Synthetic Route of 94-02-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics