Liu, Xueling; Wang, Zhiguo; Qian, Hua; Tao, Wenhua; Zhang, Ying; Hu, Chunyan; Mao, Weiwei; Guo, Qi published the artcile< Natural medicines of targeted rheumatoid arthritis and its action mechanism>, Reference of 112-63-0, the main research area is review resveratrol icariin antiiflammatory agent rheumatoid arthritis; alkaloids; autoimmune disease; flavonoids; glycosides; natural medicines; polyphenols; rheumatoid arthritis; terpenes.
A review. Rheumatoid arthritis (RA) is an autoimmune disease involving joints, with clin. manifestations of joint inflammation, bone damage and cartilage destruction, joint dysfunction and deformity, and extra-articular organ damage. As an important source of new drug mols., natural medicines have many advantages, such as a wide range of biol. effects and small toxic and side effects. They have become a hot spot for the vast number of researchers to study various diseases and develop therapeutic drugs. In recent years, the research of natural medicines in the treatment of RA has made remarkable achievements. These natural medicines mainly include flavonoids, polyphenols, alkaloids, glycosides and terpenes. Among them, resveratrol, icariin, epigallocatechin-3-gallate, ginsenoside, sinomenine, paeoniflorin, triptolide and paeoniflorin are star natural medicines for the treatment of RA. Its mechanism of treating RA mainly involves these aspects: anti-inflammation, anti-oxidation, immune regulation, pro-apoptosis, inhibition of angiogenesis, inhibition of osteoclastogenesis, inhibition of fibroblast-like synovial cell proliferation, migration and invasion. This review summarizes natural medicines with potential therapeutic effects on RA and briefly discusses their mechanisms of action against RA.
Frontiers in Immunology published new progress about Angiogenesis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.
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