In 2019,Organic Letters included an article by Kardile, Rahul Dadabhau; Liu, Rai-Shung. Recommanded Product: 4248-19-5. The article was titled 《Two Distinct Ag(I)- and Au(I)-Catalyzed Olefinations between α-Diazo Esters and N-Boc-Derived Imines》. The information in the text is summarized as follows:
In the presence of (C6F5)3PAuCl and AgNTf2 in CH2Cl2, aldimines such as (E)-PhCH:NBoc underwent regioselective and diastereoselective olefination with diazoacetates such as Et diazoacetate to yield α-aryl enamino esters such as (Z)-EtO2CCPh:CHNHBoc. Reaction of aldimines such as (E)-PhCH:NBoc with diazoacetates such as Et diazoacetate in the presence of AgOTf in toluene yielded β-aryl enamino esters such as (Z)-EtO2CCH:C(NHBoc)Ph as the major products. Reactions of a deuterated imine and diazoester and of potential aziridine and aminodiazoester intermediates were used to understand the mechanism of the reactions. The olefinations likely involve initial addition of diazo esters to metal/imine complexes followed either by Roskamp reactions to form the α-aryl-β-aminoacrylates or by the formation of silver carbenes to yield β-aryl-β-aminoacrylates. In addition to this study using tert-Butyl carbamate, there are many other studies that have used tert-Butyl carbamate(cas: 4248-19-5Recommanded Product: 4248-19-5) was used in this study.
tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Recommanded Product: 4248-19-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics