Recommanded Product: tert-Butyl carbamateIn 2021 ,《Copper(I)-catalyzed regioselective Ullmann-type coupling of primary carbamates and 5-substituted-1,2,3-triiodobenzenes: facile synthesis of 2,3-diiodinated N-aryl carbamates》 appeared in New Journal of Chemistry. The author of the article were Al-Zoubi, Raed M.; Al-Jammal, Walid K.; Al-Zoubi, Mazhar S.; McDonald, Robert; Zarour, Ahmad; Yassin, Aksam; Al-Ansari, Abdulla. The article conveys some information:
An efficient and unprecedented synthesis of 2,3-dihalo-N-phenylcarbamates through highly regioselective Ullmann-type C-N arylation reactions of 5-substituted-1,2,3-trihalobenzenes and primary carbamates was described. Remarkably, the amination reactions proceeded exclusively at the terminal positions the less sterically hindered, and the most regioactive positions. The highest yields were isolated from a combination between electron poor 1,2,3-triiodobenzenes and Et carbamates. The optimized conditions were found to be suitable for many functional groups. The first and unprecedented method to make 2,3-dihalo-N-phenylcarbamates that is efficient, general in scope, highly regioselective and gave truly remarkable precursors for other transformations.tert-Butyl carbamate(cas: 4248-19-5Recommanded Product: tert-Butyl carbamate) was used in this study.
tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Recommanded Product: tert-Butyl carbamate
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