In 2016,Shintre, Suhas A.; Ramjugernath, Deresh; Singh, Parvesh; Koorbanally, Neil A. published 《Synthesis and structure elucidation using 2D NMR and thermal coefficient investigation on amino acid tethered quinoxalines》.Magnetic Resonance in Chemistry published the findings.Quality Control of Methyl 4-fluoro-3-nitrobenzoate The information in the text is summarized as follows:
A series of aminoacid tethered quinoxalines, e. g., I, were prepared and characterized. Extensive 2D NMR studies, X-ray crystallog. and thermal coefficient investigations were used to provide a full structural elucidation of these aminoacid tethered quinoxalines. Addnl.,the d. functional theory (DFT) and mol. dynamic (MD)simulations were employed to explain the hydrogen bondingtendency and conformational flexibility of these compounds In the experiment, the researchers used many compounds, for example, Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Quality Control of Methyl 4-fluoro-3-nitrobenzoate)
Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Quality Control of Methyl 4-fluoro-3-nitrobenzoateMethyl 4-fluoro-3-nitrobenzoate is used to prepare dimethyl 3-nitro-3′,4-oxydibenzoate by reacting with 3-hydroxy-benzoic acid methyl ester.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics