Joshi, Anuradha S.; Shah, Rajvi K.; Suthar, Mona H.; Keharia, Unnati H. published the artcile< Evaluation of rationality of antimicrobial and antidiarrheal fixed dose combination available in Indian market>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is tenofovir antimicrobial fixed dose combination.
Literature reports growing concern on ever-burgeoning list of irrational fixed dose combinations (FDCs) flooding the Indian market. Current study addresses availability and rationality of two most common group of FDC used clin., i.e., antimicrobial (AM) and antidiarrheal (AD). Anal. of rationality of AM and AD, FDCs, and available in Indian market. AM and AD, FDCs listed in Indian Drug Review 2017 and 2018, were analyzed using a validated eight- point criteria tool. Out of 138 FDCs, 102 (73.91%) belonged to AM group and 36 (26.08%) belonged to AD group. Out of 102 AM FDC′s, 46 (45.09%) were rational and 56 (54.90%) were irrational. Out of 36 AD, FDCs, 10 (27.77%) were rational and 26 (72.22%) were irrational. Mean rationality score of AM and AD, FDC′s, was (7.72 ± 0.33) and (7.5 ± 0.78), resp. Anal. reveals that a number of FDCs available in Indian market is irrational.
National Journal of Physiology, Pharmacy and Pharmacology published new progress about Antimicrobial agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
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