Kim, Heebum; Kim, Sung-Gon published an article in 2022. The article was titled 《Intramolecular oxa-Mannich reaction of 1,3-dihydro-2-benzofuran-1-ol for efficient synthesis of 1-aminophthalan derivatives》, and you may find the article in Journal of the Korean Chemical Society.Product Details of 4248-19-5 The information in the text is summarized as follows:
An efficient method for the synthesis of 1-aminophthalans I (R = Ts, Boc, Cbz, POPh2) has been developed. The intramol. oxa-Mannich reaction of 1,3-dihydro-2-benzofuran-1-ols II with amines RNH2 in the presence of Cs2CO3 as a base, without using any catalyst, provided the desired 1-aminophthalans in moderate to good yields. The experimental part of the paper was very detailed, including the reaction process of tert-Butyl carbamate(cas: 4248-19-5Product Details of 4248-19-5)
tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. Left-handed and right-handed forms (mirror-image configurations, known as optical isomers or enantiomers) are possible when all the substituents on the central nitrogen atom are different (i.e., the nitrogen is chiral). With amines, there is extremely rapid inversion in which the two configurations are interconverted.Product Details of 4248-19-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics