Annibaletto, Julien; Martzel, Thomas; Levacher, Vincent; Oudeyer, Sylvain; Briere, Jean-Francois published an article in 2021. The article was titled 《Multicomponent Catalytic Enantioselective Synthesis of Isoxazolidin-5-Ones》, and you may find the article in Advanced Synthesis & Catalysis.COA of Formula: C5H11NO3 The information in the text is summarized as follows:
Herein a strategy was reported to afford a multicomponent catalytic enantioselective synthesis of β-substituted isoxazolidin-5-ones I [R = Ph, 2-naphthyl, 3-pyridyl, etc.; R1 = NMe2, N(i-Pr)2, NPh2, N-morpholinyl] via a Knoevenagel-aza-Michael-cyclocondensation (KMC) process promoted by a suited cupreine used as bifunctional organocatalyst. The hydroxamic acid component, with a sterically hindered amide moiety, proved to be key for the successful formation and transformation of the obtained original N-amide isoxazolidin-5-ones.N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3COA of Formula: C5H11NO3) was used in this study.
N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.COA of Formula: C5H11NO3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics