《Deoxygenative Deuteration of Carboxylic Acids with D2O》 was published in Angewandte Chemie, International Edition in 2019. These research results belong to Zhang, Muliang; Yuan, Xiang-Ai; Zhu, Chengjian; Xie, Jin. HPLC of Formula: 1877-71-0 The article mentions the following:
C1-Deuterated aryl and alkyl aldehydes such as 4-PhC6H4CDO and PhCH2CH2CDO were prepared chemoselectively with 58-96% deuterium incorporation by reduction of aromatic and aliphatic carboxylic acids using iridium photocatalysts, either Ph3P or Ph2OEt as an oxygen acceptor, 2,4,6-i-Pr3C6H2SH as a hydrogen atom donor, and using D2O as an inexpensive deuterium source. The method was used for the preparation of deuterated derivatives of pharmaceuticals and natural products containing aromatic carboxylic acid moieties. The method was also used for chemoselective reduction of aryl and alkyl carboxylic acids to the corresponding aldehydes using H2O as a hydrogen atom source. In the experiment, the researchers used many compounds, for example, 3-(Methoxycarbonyl)benzoic acid(cas: 1877-71-0HPLC of Formula: 1877-71-0)
3-(Methoxycarbonyl)benzoic acid(cas: 1877-71-0) belongs to esters. Esters are more polar than ethers but less polar than alcohols. HPLC of Formula: 1877-71-0 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics