《Organocatalytic Enantioselective 1,6-aza-Michael Addition of Isoxazolin-5-ones to p-Quinone Methides》 was published in European Journal of Organic Chemistry in 2020. These research results belong to Toran, Ricardo; Vila, Carlos; Sanz-Marco, Amparo; Munoz, M. Carmen; Pedro, Jose R.; Blay, Gonzalo. Formula: C7H12O3 The article mentions the following:
A thiourea-Bronsted base bifunctional catalyst allowed the enantioselective 1,6-aza-Michael addition of isoxazolin-5-ones to p-quinone methides to give isoxazolin-5-ones having a chiral diarylmethyl moiety attached to the N atom with fair to good yields and enantiomeric excesses. To the best of our knowledge this reaction represents the first example of enantioselective N-alkylation of isoxazolin-5-ones as well as the first example of enantioselective 1,6-aza-Michael reaction involving p-quinone methides. After reading the article, we found that the author used Ethyl 3-oxopentanoate(cas: 4949-44-4Formula: C7H12O3)
Ethyl 3-oxopentanoate(cas: 4949-44-4) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Formula: C7H12O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics