Lv, Leiyang; Li, Zhiping published the artcile< Cycloalkylation of C(sp3)-H Bond with Neighboring Carboxylic Acid as Traceless Activating Group>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is cycloalkylation carbon hydrogen bond carboxylic acid traceless activating group.
Selective functionalization of an inert C(sp3)-H bond is one of the cutting-edge challenges in chem. synthesis. A novel strategy for selective C(sp3)-H bond cycloalkylation is developed with neighboring carboxylic acid as a traceless activating group. Primary and secondary alkyl carboxylic acids undergo decarboxylation/α-C(sp3)-H cleavage/cycloalkylation to give the five-membered cyclization products, while tertiary acids undergo decarboxylation/β-C(sp3)-H cleavage/cycloalkylation to generate the six-membered cyclization products.
Journal of Organic Chemistry published new progress about Aliphatic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics