Enuh, Blaise Manga; Aytar Celik, Pinar published the artcile< Insight into the biotechnology potential of Alicyclobacillus tolerans from whole genome sequence analysis and genome-scale metabolic network modeling.>, HPLC of Formula: 112-63-0, the main research area is Alicyclobacillus carbohydrates bioinformatics biotechnol network modeling; Acidophiles; Alicyclobacillus tolerans; Extreme environment; Genome-scale metabolic network model; Iron oxidation; Whole-genome sequence.
Extremophilic bacteria have numerous uncovered biotechnol. potentials. Acidophilic bacteria are important iron oxidizers that are valuable in bioleaching and in studying extreme environments on earth and in space. Despite their obvious potential, little is known about the genetic traits that underpin their metabolic functions, which are equally poorly understood from a mechanistic perspective. Novel bioinformatics and computational biol. pipelines can be used to analyze whole genomes to obtain insights into the phenotypic potential of organisms as well as develop a math. model representation of metabolism Whole-genome sequence anal. and a genome-scale metabolic network model was curated for an iron-oxidizing bacterium initially isolated from an acid mine drainage in Turkey, previously identified as Alicyclobacillus tolerans. The genome contained a high proportion of genes for energy generation from carbohydrates, amino acids synthesis and conversion, nucleic acid metabolism and repair which contribute to robust adaptation to their extreme environments. Several candidate genes for pyrite metabolism, iron uptake, regulation and storage, as well as genes for resistance to important heavy metals were annotated. A curated genome-scale metabolic network anal. accurately predicted facultative anaerobic growth, heterotrophic characteristics, and growth on a wide variety of carbon sources. This is the first in-depth in silico anal. of A. tolerans to the best of our knowledge which is expected to lay the groundwork for future research and drive innovations in environmental microbiol. and biotechnol. applications. The genomic data and mechanistic framework will have applications in biomining, synthetic geomicrobiol. on earth, as well as for space exploration and settlement.
Journal of Microbiological Methods published new progress about Alicyclobacillus tolerans. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics