《Design, synthesis, and evaluation of novel 3-, 4-substituted, and 3,4-di substituted quinazoline derivatives as antimicrobial agents》 was published in Revista de Chimie (Bucharest, Romania) in 2020. These research results belong to El-Essawy, Farag A.; Alharthi, Abdulrahman I.; Alotaibi, Mshari A.; Wahba, Nancy E.; Boshta, Nader M.. Computed Properties of C8H14O4 The article mentions the following:
A novel series of 3-, 4-substituted, and 3,4-di substituted quinazoline derivatives were prepared via various cyclized regents and most of the newly prepared compounds evaluated for their antimicrobial activities in vitro against Gram-pos., Gram-neg. bacterial strains and fungi strains. The structures of the quinazoline derivatives have been confirmed using spectroscopic analyses (IR, NMR, and EI-MS). Some of the synthesized derivatives displayed a moderate antimicrobial activity in comparison with reference drugs, for example compounds 13d, 15a, 17b, 18b, 18d, 25, and 29a-c. Among the synthesized compounds, the pyrimidoqunazoline derivative 6c elicited the highest activity. In the part of experimental materials, we found many familiar compounds, such as Diethyl 2-methylmalonate(cas: 609-08-5Computed Properties of C8H14O4)
Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Computed Properties of C8H14O4
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