Shogren-Knaak, Michael A’s team published research in Tetrahedron Letters in 1998-11-05 | 112-63-0

Tetrahedron Letters published new progress about Affinity purification. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Shogren-Knaak, Michael A.; Imperiali, Barbara published the artcile< A reversible affinity tag for the purification of N-glycolyl capped peptides>, Formula: C19H34O2, the main research area is affinity tag reversible biotin based purification N glycolyl peptide.

A reversible biotin affinity tag, 2-[6-(biotinylamino)caproyloxy]acetic acid (I), has been generated for the efficient purification of peptides requiring N-terminal derivatization. This methodol. is compatible with solid phase peptide synthesis techniques. For example, HOCH2CO-FSRSDELAKLLRLHAG-NH2 was obtained via the following steps: solid-phase synthesis in an automated peptide synthesizer, capping with reagent I, isolation by avidin-based affinity column chromatog. and cleavage of I’s ester bond under mildly basic conditions to give the the final N-glycolyl peptide.

Tetrahedron Letters published new progress about Affinity purification. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics