Wu, Xiaowei; Iwata, Takayuki; Scharf, Adam; Qin, Tian; Reichl, Kyle D.; Porco, John A. published the artcile< Asymmetric Synthesis of Gonytolide A: Strategic Use of an Aryl Halide Blocking Group for Oxidative Coupling>, Category: esters-buliding-blocks, the main research area is asym gonytolide A synthesis aryl halide oxidative coupling.
The first synthesis of the chromanone lactone dimer gonytolide A was achieved employing vanadium(V)-mediated oxidative coupling of the monomer gonytolide C. An o-bromine blocking group strategy was employed to favor para-para coupling and to enable kinetic resolution of (±)-gonytolide C. Asym. conjugate reduction enabled practical kinetic resolution of a chiral, racemic precursor and the asym. synthesis of (+)-gonytolide A and its atropisomer.
Journal of the American Chemical Society published new progress about Atropisomers. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics