Saito, Seiki; Ishikawa, Teruhiko; Kuroda, Akiyoshi; Koga, Kazuya; Moriwake, Toshio published the artcile< A revised mechanism for chemoselective reduction of esters with borane-dimethyl sulfide complex and catalytic sodium tetrahydroborate directed by adjacent hydroxyl group>, Related Products of 617-55-0, the main research area is ester reduction chemoselectivity borane dimethyl sulfide; sodium borohydride reduction ester stereochem; chiral synthon.
The plausible mechanism for the reduction of the ester groups with a strong preference for one located α to the hydroxyl groups of (S)-malates and (R,R)-tartrate-based derivatives has been proposed together with some results with regard to its applications to the synthesis of chiral synthons. Thus, reduction of di-Et (S)-maleate with BH3·SMe2 in THF in the presence of catalytic NaBH4 gave 97% Et (3S)-3,4-dihydroxybutanoate.
Tetrahedron published new progress about Chiral synthons. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Related Products of 617-55-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics