《Asymmetric organocatalytic multicomponent reactions for efficient construction of bicyclic compounds bearing bisacetal and isoxazolidine moieties》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Pei, Jun-Ping; Lv, Xue-Jiao; Peng, Chen-Jun; Liu, Yan-Kai. Safety of N-tert-Butoxycarbonylhydroxylamine The article mentions the following:
An organocatalytic multicomponent reaction of N-protected hydroxylamines R1NHOH (R1 = Boc, Troc, Cbz), acrolein and acetal-containing enones (MeO)2CHCH:CHR2 (R2 = O2N, PhCO, PhCH:CHCO, etc.) has been developed. Bisacetal-containing bicyclic isoxazolidine derivatives bearing four continuous stereocenters I were formed with excellent stereoselectivities. A plausible reaction pathway was proposed based on 18O-labeling control experiments In addition to this study using N-tert-Butoxycarbonylhydroxylamine, there are many other studies that have used N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3Safety of N-tert-Butoxycarbonylhydroxylamine) was used in this study.
N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).Safety of N-tert-Butoxycarbonylhydroxylamine
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