Becker, Jeffrey M.; Wilchek, Meir; Katchalski, Ephraim published the artcile< Irreversible inhibition of biotin transport in yeast by biotinyl-p-nitrophenyl ester>, Reference of 112-63-0, the main research area is biotin transport Saccharomyces inactivator; biotinylnitrophenyl yeast biotin transport.
Biotinyl-p-nitrophenyl ester (I) [33755-53-2] at .geq.10-7M irreversibly inactivated biotin [58-85-5] transport in Saccharomyces cerevisiae. The extent of inactivation increased with time, implying that I reacts with a transport component(s) to yield a covalently-bound biotinyl derivative I did not affect the transport of lysine [56-87-1], aspartic acid [56-84-8], or L-sorbose [87-79-6]. Inactivation of biotin transport by I was partially prevented in the presence of high concentrations of biotin (0.5mM). Biotinyl-p-nitroanilide [33755-54-3], (0.1mM) and acetyl-p-nitrophenyl ester (0.1mM) did not affect biotin transport when added to S. cerevisiae suspensions.
Proceedings of the National Academy of Sciences of the United States of America published new progress about Saccharomyces cerevisiae. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics