《The toxicity of some fluoroaromatic compounds》 was published in Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Biologo-Meditsinskikh Nauk in 1967. These research results belong to Lapik, A. S.; Zimina, L. N.. Safety of Ethyl 2,3,4,5,6-pentafluorobenzoate The article mentions the following:
The oral LD50 of the following compounds were determined for white mice: benzaldehyde 1240, pentafluorobenzaldehyde 320, benzoic acid 2800, pentafluorobenzoic acid 2500, acetophenone 970, pentafluoroacetophenone 850, decafluorohydrobenzoin 485, dinitrodecafluorohydrobenzoin 5000, terephthalic acid 585, tetrafluoroterephthalic acid 350, di-Me tetrafluoroterephthalate 870, phthalic acid 560, tetrafluorophthalic acid (I) 320, di-Me I 780, pentafluorobromobenzene 959, ω-bromoacetophenone 690, ω-bromopentafluoroacetophenone 350, Et pentafluorobenzoate 1700, benzophenone 1250, decafluorobenzophenone 960, decafluorobenzhydrol 1350, pentafluorobenzhydrol 1750, ester of decafluorobenzhydrol and HNO3 1750, tris(pentafluorophenyl)methane 1625, benzene 400, pentafluorobenzene 710, pentafluorochlorobenzene 1250, octafluoronaphthalene 670, hexafluoro-1,4-naphthoquinone 450, pentafluoropyridine 280, fluoranil 420 mg./kg. The toxic symptoms were generally similar: decreased motor activity, loss of coordination, paralysis, and death. The benzene derives. had a narcotic effect and octafluoronaphthalene and pentafluoropyridine caused convulsions. The experimental process involved the reaction of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Safety of Ethyl 2,3,4,5,6-pentafluorobenzoate)
Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Safety of Ethyl 2,3,4,5,6-pentafluorobenzoate They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics