《Chemoselective 18F-incorporation into pyridyl acyltrifluoroborates for rapid radiolabelling of peptides and proteins at room temperature》 was written by Chiotellis, Aristeidis; Ahmed, Hazem; Betzel, Thomas; Tanriver, Matthias; White, Christopher J.; Song, Haewon; Da Ros, Sara; Schibli, Roger; Bode, Jeffrey W.; Ametamey, Simon M.. Electric Literature of C5H11NO3 And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:
A new prosthetic group is reported for 18F-labeling of peptides and proteins based on the chemoselective ligation of potassium acyltrifluoroborates (KATs) and hydroxylamines without any detectable 18F/19F isotope exchange at the acyltrifluoroborate moiety. The new building block is appended via a common amide bond at room temperature with no need for protecting groups which enables an effective orthogonal 18F-radiolabelling. In addition to this study using N-tert-Butoxycarbonylhydroxylamine, there are many other studies that have used N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3Electric Literature of C5H11NO3) was used in this study.
N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Electric Literature of C5H11NO3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics