Bikman, Benjamin T.; Shimy, Kim J.; Apovian, Caroline M.; Yu, S.; Saito, Erin R.; Walton, Chase M.; Ebbeling, Cara B.; Ludwig, David S. published the artcile< A high-carbohydrate diet lowers the rate of adipose tissue mitochondrial respiration>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is adipose tissue mitochondrial respiration diet rate.
Adipocyte mitochondrial respiration may influence metabolic fuel partitioning into oxidation vs. storage, with implications for whole-body energy expenditure. Although insulin has been shown to influence mitochondrial respiration, the effects of dietary macronutrient composition have not been well characterized. The aim of this exploratory study was to test the hypothesis that a high-carbohydrate diet lowers the oxygen flux of adipocyte mitochondria ex vivo. Among participants in a randomized-controlled weight-loss maintenance feeding trial, those consuming a high-carbohydrate diet (60% carbohydrate as a proportion of total energy, n = 10) had lower rates of maximal adipose tissue mitochondrial respiration than those consuming a moderate-carbohydrate diet (40%, n = 8, p = 0.039) or a low-carbohydrate diet (20%, n = 9, p = 0.005) after 10 to 15 wk. This preliminary finding may provide a mechanism for postulated calorie-independent effects of dietary composition on energy expenditure and fat deposition, potentially through the actions of insulin on fuel partitioning.
European Journal of Clinical Nutrition published new progress about Adipose tissue. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
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Ester – an overview | ScienceDirect Topics