Ahmadi, Vahid’s team published research in Chemical Communications (Cambridge, United Kingdom) in 2021 | 112-63-0

Chemical Communications (Cambridge, United Kingdom) published new progress about Antiviral agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Ahmadi, Vahid; Nie, Chuanxiong; Mohammadifar, Ehsan; Achazi, Katharina; Wedepohl, Stefanie; Kerkhoff, Yannic; Block, Stephan; Osterrieder, Klaus; Haag, Rainer published the artcile< One-pot gram-scale synthesis of virucidal heparin-mimicking polymers as HSV-1 inhibitors>, Synthetic Route of 112-63-0, the main research area is virucidal heparin mimicking polymer antiviral agent Herpes simplex virus.

A straightforward and gram-scale synthesis method was developed to engineer highly sulfated hyperbranched polyglycerol bearing sulfated alkyl chains. The compounds with shorter alkyl chains showed multivalent virustatic inhibition against herpes simplex virus type 1 (HSV-1), similar to heparin. In contrast, the compound with the longest alkyl chains irreversibly inhibited the virus.

Chemical Communications (Cambridge, United Kingdom) published new progress about Antiviral agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics