Shibata, Norio; Ishimaru, Takehisa; Nakamura, Mai; Toru, Takeshi published the artcile< 20-Deoxy-20-fluorocamptothecin: Design and synthesis of camptothecin isostere>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is fluorocamptothecin asym synthesis stereoselective fluorination Cinchona alkaloid catalyst; stereoselective electrophilic fluorination deoxycamptothecin Cinchona alkaloid catalyst.
(±)-20-Deoxy-20-fluorocamptothecin (I) was synthesized as an isosteric analog of camptothecin. The use of Selectfluor or N-fluorobenzenesulfonimide and Cinchona alkaloid catalysts for the electrophilic fluorination of (±)-20-deoxycamptothecin (II) yields the target compound Enantioselective fluorination of II was also achieved using previously described Cinchona alkaloids/Selectfluor combination to provide both enantiomers of I with 88% ee and 81% ee, resp.
Synlett published new progress about Cinchona alkaloids Role: CAT (Catalyst Use), USES (Uses). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics