Larsen, Rolf Olaf; Aksnes, Gunnar published the artcile< Kinetic study of the Horner reaction. I>, Formula: C19H34O2, the main research area is Horner reaction phosphonate benzaldehyde kinetics; LFER Horner reaction.
The rates of the Horner-reaction of 5 phosphonates (EtO)2P(O)CH2R (R = CO2Et, CN, p-O2NC6H4) and I (Q = CH2CH2, CHMe) with NaOEt and various p- and m-substituted benzaldehydes, and ethanol as solvent, are reported. The kinetics of the reactions are overall third order, first order in phosphonate, ethoxide, and aldehyde, resp. The reaction is accelerated by electron-withdrawing substituents in the benzaldehyde, giving a reaction constant, ρ, of ∼+2.0. The 5-membered cyclic phosphonate reacts ∼20 times faster than its acyclic analog. The rate difference is attributed to a considerable release in ring strain upon passing from the tetrahedral to the pentacoordinate state in the intermediate of the cyclic phosphonate.
Phosphorus and Sulfur and the Related Elements published new progress about Linear free energy relationship. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.
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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics