Computed Properties of C10H10O2. Authors Adnan, M; Siddiqui, AJ; Hamadou, WS; Patel, M; Ashraf, SA; Jamal, A; Awadelkareem, AM; Sachidanandan, M; Snoussi, M; De Feo, V in MDPI published article about in [Adnan, Mohd; Siddiqui, Arif Jamal; Hamadou, Walid Sabri; Jamal, Arshad; Snoussi, Mejdi] Univ Hail, Dept Biol, Coll Sci, Hail 2440, Saudi Arabia; [Patel, Mitesh] Veer Narmad South Gujarat Univ, Dept Biosci, Bapalal Vaidya Bot Res Ctr, Surat 395007, India; [Ashraf, Syed Amir; Awadelkareem, Amir Mahgoub] Univ Hail, Dept Clin Nutr, Coll Appl Medial Sci, Hail 2440, Saudi Arabia; [Sachidanandan, Manojkumar] Univ Hail, Dept Oral Radiol, Coll Dent, Hail 2440, Saudi Arabia; [Snoussi, Mejdi] Univ Monastir, High Inst Biotechnol, Lab Genet Biodivers & Valorisat Bioresources, Monastir 5000, Tunisia; [De Feo, Vincenzo] Univ Salerno, Dept Pharm, Via Giovanni Paolo II,132, I-84084 Salerno, Italy in 2021.0, Cited 89.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4
In this study, we investigated the bioactive potential (antibacterial and antioxidant), anticancer activity and detailed phytochemical analysis of Selaginella repanda (S. repanda) ethanolic crude extract for the very first time using different in vitro approaches. Furthermore, computer-aided prediction of pharmacokinetic properties and safety profile of the identified phytoconstituents were also employed in order to provide some useful insights for drug discovery. S. repanda, which is a rich source of potent natural bioactive compounds, showed promising antibacterial activity against the tested pathogenic bacteria (S. aureus, P. aeruginosa, E. coli and S. flexneri). The crude extract displayed favorable antioxidant activity against both 2,2-diphenyl-1-picrylhydrazyl (DPPH) (IC50 = 231.6 mu g/mL) and H2O2 (IC50 = 288.3 mu g/mL) molecules. S. repanda also showed favorable and effective anticancer activity against all three malignant cancer cells in a dose/time dependent manner. Higher activity was found against lung (A549) (IC50 = 341.1 mu g/mL), followed by colon (HCT-116) (IC50 = 378.8 mu g/mL) and breast (MCF-7) (IC50 = 428.3 mu g/mL) cancer cells. High resolution-liquid chromatography-mass spectrometry (HR-LC-MS) data of S. repanda crude extract revealed the presence of diverse bioactive/chemical components, including fatty acids, alcohol, sugar, flavonoids, alkaloids, terpenoids, coumarins and phenolics, which can be the basis and major cause for its bioactive potential. Therefore, achieved results from this study confirmed the efficacy of S. repanda and a prospective source of naturally active biomolecules with antibacterial, antioxidant and anticancer potential. These phytocompounds alone with their favorable pharmacokinetics profile suggests good lead and efficiency of S. repanda with no toxicity risks. Finally, further in vivo experimental investigations can be promoted as probable candidates for various therapeutic functions, drug discovery and development.
Welcome to talk about 103-26-4, If you have any questions, you can contact Adnan, M; Siddiqui, AJ; Hamadou, WS; Patel, M; Ashraf, SA; Jamal, A; Awadelkareem, AM; Sachidanandan, M; Snoussi, M; De Feo, V or send Email.. Computed Properties of C10H10O2
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Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
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