Recommanded Product: Methyl 3-phenylpropionate. I found the field of Chemistry very interesting. Saw the article Reductive Allylic Defluorinative Cross-Coupling Enabled by Ni/Ti Cooperative Catalysis published in 2019.0, Reprint Addresses Wang, C (corresponding author), Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Dept Chem, Ctr Excellence Mol Synth, 96 Jinzhai Rd, Hefei 230026, Anhui, Peoples R China.. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate.
Unactivated alkyl chlorides are abundant building blocks in organic synthesis, but they have been rarely engaged in cross-electrophile coupling. Herein, we report a Ni/Ti-cocatalyzed reductive allylic defluorinative cross -coupling between trifluoromethyl alkenes and unactivated alkyl chlorides and bromides, enabling the efficient preparation of diverse functional-group-rich gem-difluoroalkenes. Notably, synthesis of the gem-difluoroalkene analogues of azaperone, haloperidol, and benperidol was also accomplished using our method as a key step.
Welcome to talk about 103-25-3, If you have any questions, you can contact Lin, ZY; Lan, Y; Wang, C or send Email.. Recommanded Product: Methyl 3-phenylpropionate
Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics