Month: November 2021

An article Identification of Cytotoxic Flavor Chemicals in Top-Selling Electronic Cigarette Refill Fluids WOS:000459698900043 published article about BRONCHIOLITIS OBLITERANS; MICROWAVE-POPCORN; TOXICITY; LIQUIDS; CINNAMALDEHYDE; PRODUCTS; FRUIT in [Hua, My; Omaiye, Esther E.] Univ Calif Riverside, Environm Toxicol Grad Program, Riverside, CA 92521 USA; [Luo, Wentai; McWhirter, Kevin J.; Pankow, James F.] Portland State Univ, Dept Chem, Portland, OR 97207 USA; [Luo, Wentai; McWhirter, Kevin J.; Pankow, James F.] Portland State Univ, Dept Civil & Environm Engn, Portland, OR 97207 USA; [Hua, My; Omaiye, Esther E.; Talbot, Prue] Univ Calif Riverside, Dept Mol Cell & Syst Biol, Riverside, CA 92521 USA in 2019, Cited 39. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Application In Synthesis of Methyl 3-phenyl-2-propenoate

We identified the most popular electronic cigarette (EC) refill fluids using an Internet survey and local and online sales information, quantified their flavor chemicals, and evaluated cytotoxicities of the fluids and flavor chemicals. Berries/Fruits/Citrus was the most popular EC refill fluid flavor category. Twenty popular EC refill fluids were purchased from local shops, and the ingredient flavor chemicals were identified and quantified by gas chromatography-mass spectrometry. Total flavor chemical concentrations ranged from 0.6 to 27.9 mg/ml, and in 95% of the fluids, total flavor concentration was greater than nicotine concentration. The 20 most popular refill fluids contained 99 quantifiable flavor chemicals; each refill fluid contained 22 to 47 flavor chemicals, most being esters. Some chemicals were found frequently, and several were present in most products. At a 1% concentration, 80% of the refill fluids were cytotoxic in the MTT assay. Six pure standards of the flavor chemicals found at the highest concentrations in the two most cytotoxic refill fluids were effective in the MTT assay, and ethyl maltol, which was in over 50% of the products, was the most cytotoxic. These data show that the cytotoxicity of some popular refill fluids can be attributed to their high concentrations of flavor chemicals.

Application In Synthesis of Methyl 3-phenyl-2-propenoate. Welcome to talk about 103-26-4, If you have any questions, you can contact Hua, M; Omaiye, EE; Luo, WT; McWhirter, KJ; Pankow, JF; Talbot, P or send Email.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Authors Rumyantsev, AV; Pichugov, AV; Bushkov, NS; Aleshin, DY; Strelkova, TV; Lependina, OL; Zhizhko, PA; Zarubin, DN in ROYAL SOC CHEMISTRY published article about in [Rumyantsev, Andrey, V; Pichugov, Andrey, V; Bushkov, Nikolai S.; Aleshin, Dmitry Yu; Strelkova, Tatyana, V; Lependina, Olga L.; Zhizhko, Pavel A.; Zarubin, Dmitry N.] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Vavilov Str 28, Moscow 119991, Russia; [Rumyantsev, Andrey, V; Bushkov, Nikolai S.] Moscow MV Lomonosov State Univ, Dept Chem, Vorobevy Gory 1, Moscow 119991, Russia; [Pichugov, Andrey, V; Aleshin, Dmitry Yu] D Mendeleev Univ Chem Technol Russia, Higher Chem Coll, Miusskaya Sq 9, Moscow 125047, Russia in 2021.0, Cited 33.0. Formula: C13H8O2. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9

We report the first examples of direct imidation of lactones giving the corresponding cyclic imidates via oxo/imido heterometathesis with N-sulfinylamines catalysed by a well-defined silica-supported Ti imido complex.

Welcome to talk about 2005-10-9, If you have any questions, you can contact Rumyantsev, AV; Pichugov, AV; Bushkov, NS; Aleshin, DY; Strelkova, TV; Lependina, OL; Zhizhko, PA; Zarubin, DN or send Email.. Formula: C13H8O2

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Intra-Articular Route for the System of Molecules 14G1862 fromCentella asiatica: Pain Relieving and Protective Effects in a Rat Model of Osteoarthritis WOS:000553482000001 published article about KNEE OSTEOARTHRITIS; NITRIC-OXIDE; MATRIX METALLOPROTEINASES; ARTICULAR CHONDROCYTES; RHEUMATOID-ARTHRITIS; SUPEROXIDE-DISMUTASE; HYDROGEN-PEROXIDE; SYNOVIAL-FLUID; EXPRESSION; MANAGEMENT in [Micheli, Laura; Di Cesare Mannelli, Lorenzo; Cinci, Lorenzo; D’Ambrosio, Mario; Luceri, Cristina; Ghelardini, Carla] Univ Florence, Dept Neurosci Psychol Drug Res & Child Hlth NEURO, Pharmacol & Toxicol Sect, Viale Gaetano Pieraccini 6, I-50139 Florence, Italy; [Mattoli, Luisa; Tamimi, Sara; Flamini, Enrico; Garetto, Stefano; Lucci, Jacopo; Giovagnoni, Emiliano] Aboca SpA Soc Agr, Innovat & Med Sci Div, Loc Aboca 20, I-52037 Sansepolcro, Italy; [Garetto, Stefano; Lucci, Jacopo] Nat Biomed SpA, Loc Aboca 20, I-52037 Sansepolcro, Italy in 2020.0, Cited 74.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. SDS of cas: 103-26-4

Current pharmacological therapies for the management of chronic articular diseases are far from being satisfactory, so new strategies need to be investigated. We tested the intra-articular pain relieving properties of a system of molecules from a characterizedCentella asiaticaextract (14G1862) in a rat model of osteoarthritis induced by monoiodoacetate (MIA). 14G1862 (0.2-2 mg mL(-1)) was intra-articularly (i.a.) injected 7 days after MIA, behavioural and histological evaluations were performed 14, 30 and 60 days after treatments. Moreover, the effect of 14G1862 on nitrate production and iNOS expression in RAW 264.7 macrophages stimulated with LPS was assessed. In vitro, 14G1862 treatment attenuated LPS-induced NO production and iNOS expression in a comparable manner to celecoxib. In vivo, 14G1862 significantly reduced mechanical allodynia and hyperalgesia, spontaneous pain and motor alterations starting on day 14 up to day 60. The efficacy was higher or comparable to that evoked by triamcinolone acetonide (100 mu g i.a.) used as reference drug. Histological evaluation highlighted the improvement of several morphological parameters in MIA + 14G1862-treated animals with particularly benefic effects on joint space and fibrin deposition. In conclusion, i.a. treatment withCentella asiaticais a candidate to be a novel effective approach for osteoarthritis therapy.

Welcome to talk about 103-26-4, If you have any questions, you can contact Micheli, L; Mannelli, LD; Mattoli, L; Tamimi, S; Flamini, E; Garetto, S; Lucci, J; Giovagnoni, E; Cinci, L; D’Ambrosio, M; Luceri, C; Ghelardini, C or send Email.. SDS of cas: 103-26-4

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2020.0 ORG LETT published article about C-F BOND; H DUAL ACTIVATION; CASCADE ANNULATION; CARBOXYLIC-ACIDS; ARYL MIGRATION; ARYLATION; ACCESS; DERIVATIVES; EXTENSION; NITRILES in [Pan, Cheng; Wang, Limin; Han, Jianwei] East China Univ Sci & Technol, Key Lab Adv Mat, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China; [Pan, Cheng; Wang, Limin; Han, Jianwei] East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China; [Han, Jianwei] Chinese Acad Sci, Shanghai Hong Kong Joint Lab Chem Synth, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China in 2020.0, Cited 68.0. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9. HPLC of Formula: C13H8O2

By using 2-fluoro-substituted diaryliodonium salts, a novel benzocylization has been accomplished for the synthesis of 3,4-benzocoumarin derivatives via a cascade of ortho-arylation and defluorination in the presence of palladium catalysts. The reaction exhibits a broad compatibility of readily available aromatic acids with an excellent level of site-selectivity. Mechanistic investigations revealed a unique reactivity of carboxylic acid directed arylation by followed nucleophilic substitution of aromatic fluoride in the present system.

HPLC of Formula: C13H8O2. Bye, fridends, I hope you can learn more about C13H8O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Production of Methyl p-Hydroxycinnamate by Selective Tailoring of Herbaceous Lignin Using Metal-Based Deep Eutectic Solvents (DES) as Catalyst WOS:000577113500041 published article about SUGARCANE BAGASSE; DIETHYL MALEATE; DEPOLYMERIZATION; EFFICIENT; DELIGNIFICATION; OXIDATION; CLEAVAGE; MONOMERS; BIOMASS; PHENOL in [Li, Zhang-min; Long, Jin-xing; Zeng, Qiang; Wu, Yuan-hao; Cao, Ming-long; Liu, Si-jie; Li, Xue-hui] South China Univ Technol, State Key Lab Pulp & Paper Engn, Sch Chem & Chem Engn, Guangzhou 510640, Peoples R China; [Li, Zhang-min] Jiangxi Normal Univ, Coll Chem & Chem Engn, Nanchang 330022, Jiangxi, Peoples R China in 2020, Cited 39. The Name is Methyl 2,2-dimethoxyacetate. Through research, I have a further understanding and discovery of 89-91-8. HPLC of Formula: C5H10O4

Catalytic conversion of lignin to versatile aromatic compounds is attracting increasing attention. However, it is highly desirable but challenging to produce a specific chemical with high yield through lignin depolymerization in a one-pot process because of the complex structure of the lignin molecule (mainly composed of H, G, and S units). In this study, a series of metal-based deep eutectic solvents (M-DESs) were prepared and used for the catalytic tailoring of lignin H units to produce value-added methyl p-hydroxycinnamate (MPC). In particular, M-DES ChCl[FeCl3](2) showed excellent catalytic performance for the selective production of MPC as the sole product with high yield and selectivity (105.8 mg g(-1) and 74.1%, respectively). Extensive characterizations using 2D HSQC NMR, C-13 NMR, and GPC demonstrated that MPC was obtained from the selective tailoring of p-coumaric acid (pCA) units via the cleavage of ester bonds in lignin. Furthermore, M-DES ChCl[FeCl3](2) also exhibited efficiency to other herbaceous lignins, and showed excellent recyclability. Therefore, this work provides an effective strategy for the valorization of lignin.

HPLC of Formula: C5H10O4. Bye, fridends, I hope you can learn more about C5H10O4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Patent; U C B, Societe Anonyme; US4041077; (1977); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2019 CHEMISTRYSELECT published article about INTRAMOLECULAR-CHARGE-TRANSFER; TRIARYLAMINES; SEPARATION; STATES; DONOR in [Ohmura, Satoshi D.; Ueno, Masaharu; Miyoshi, Norikazu] Tokushima Univ, Dept Nat Sci, Grad Sch Technol Ind & Social Sci, Minami Josanjima 2-1, Tokushima, Japan; [Ohmura, Satoshi D.; Yamana, Keisuke; Ueno, Masaharu; Miyoshi, Norikazu] Tokushima Univ, Dept Chem, Fac Integrated Arts & Sci, Minami Josanjima 1-1, Tokushima, Japan in 2019, Cited 24. The Name is Dimethyl 5-aminoisophthalate. Through research, I have a further understanding and discovery of 99-27-4. Quality Control of Dimethyl 5-aminoisophthalate

A series of triphenylamine derivatives bearing a methoxycarbonyl group at the meta-position of the benzene ring were synthesized. The structural and physical properties based on the introduction of the methoxycarbonyl group into benzene ring were investigated by single crystal X-ray diffraction, computational studies, and spectroscopic methods. It was revealed that the methoxycarbonyl group has not only structural regulations but also modifications of the electronic properties of the pi-conjugated moieties.

About Dimethyl 5-aminoisophthalate, If you have any questions, you can contact Ohmura, SD; Yamana, K; Ueno, M; Miyoshi, N or concate me.. Quality Control of Dimethyl 5-aminoisophthalate

Reference:
Patent; ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC.; WO2004/14881; (2004); A2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Pd-Catalyzed Selective Carbonylation of gem-Difluoroalkenes: A Practical Synthesis of Difluoromethylated Esters published in 2019.0. SDS of cas: 103-25-3, Reprint Addresses Beller, M (corresponding author), Univ Rostock, Leibniz Inst Katalyse, Albert Einstein Str 29a, D-18059 Rostock, Germany.. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate

The first catalyst for the alkoxycarbonylation of gem-difluoroalkenes is described. This novel catalytic transformation proceeds in the presence of Pd(acac)(2)/1,2-bis((di-tert-butylphosphan-yl)methyl)benzene (btbpx) (L4) and allows for an efficient and straightforward access to a range of difluoromethylated esters in high yields and regioselectivities. The synthetic utility of the protocol is showcased in the practical synthesis of a Cyclandelate analogue using this methodology as the key step.

SDS of cas: 103-25-3. Welcome to talk about 103-25-3, If you have any questions, you can contact Liu, JW; Yang, J; Ferretti, F; Jackstell, R; Beller, M or send Email.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Authors Munoz, A; Leo, P; Orcajo, G; Martinez, F; Calleja, G in WILEY-V C H VERLAG GMBH published article about METAL-ORGANIC FRAMEWORK; WATER-ADSORPTION; EFFICIENT; ACIDS; MOFS in [Munoz, Antonio; Orcajo, Gisela; Calleja, Guillermo] Rey Juan Carlos Univ, Dept Chem Energy & Mech Technol, C Tulipan S-N, Mostoles 28933, Spain; [Leo, Pedro; Martinez, Fernando] Rey Juan Carlos Univ, Dept Chem & Environm Technol, C Tulipan S-N, Mostoles 28933, Spain in 2019, Cited 41. Recommanded Product: Dimethyl 5-aminoisophthalate. The Name is Dimethyl 5-aminoisophthalate. Through research, I have a further understanding and discovery of 99-27-4

Guillermo Calleja and co-workers from @urjc describe URJC-1-MOF as a new heterogeneous recyclable catalyst for c-heteroatom coupling reactions The capacity of copper-based URJC-1-MOF as a MOF catalyst in cross-coupling reactions has been evaluated, focusing on the Chan-Lam-Evans arylation-type reactions on amines and alcohols without extra additives or ligands. The extraordinary chemical and structural stability of URJC-1-MOF and its good specific surface, make this material a promising alternative to homogeneous Cu (II) catalysts for cross-coupling reactions. URJC-1-MOF showed a remarkable catalytic activity for cross-coupling C-N and C-O reactions, higher than other heterogeneous and homogeneous copper-based catalyst, such as CuO, HKUST-1, Cu-MOF-74, Cu(OAc)(2) and CuSO4.5H(2)O. Moreover, its easy recovery by simple filtration and reusability in successive runs without any loss of activity and stability, demonstrates the potential of URJC-1-MOF as an alternative catalyst for this kind of reactions in different chemical media of industrial interest.

Bye, fridends, I hope you can learn more about C10H11NO4, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: Dimethyl 5-aminoisophthalate

Reference:
Patent; ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC.; WO2004/14881; (2004); A2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article A robust etb-type metal-organic framework showing polarity-exclusive adsorption of acetone over methanol for their azeotropic mixture published in 2019. Formula: C10H11NO4, Reprint Addresses Ling, Y (corresponding author), Fudan Univ, Shanghai Key Lab Mol Catalysis & Innovat Mat, Dept Chem, Shanghai 200438, Peoples R China.. The CAS is 99-27-4. Through research, I have a further understanding and discovery of Dimethyl 5-aminoisophthalate

We report a robust and rigid etb-type metal-organic framework, in which its pore surface is decorated with flexible ethoxyl groups. It shows unprecedentedly selective adsorption of acetone (E-N(T) value of 0.355, kinetic diameter of 4.6 angstrom) over methanol (E-N(T) value of 0.762, kinetic diameter of 3.6 angstrom) for their azeotropic mixture.

Welcome to talk about 99-27-4, If you have any questions, you can contact Hu, H; Zhu, JX; Yang, FL; Chen, ZX; Deng, ML; Weng, LH; Ling, Y; Zhou, YM or send Email.. Formula: C10H11NO4

Reference:
Patent; ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC.; WO2004/14881; (2004); A2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application In Synthesis of Methyl 3-phenyl-2-propenoate. Authors Krizkovska, B; Kumar, R; Rehorova, K; Sykora, D; Dobiasova, S; Kucerova, D; Tan, MC; Linis, V; Oyong, G; Ruml, T; Lipov, J; Viktorova, J in MDPI published article about in [Krizkovska, Bara; Kumar, Rohitesh; Rehorova, Katerina; Dobiasova, Simona; Kucerova, Denisa; Ruml, Tomas; Lipov, Jan; Viktorova, Jitka] Univ Chem & Technol Prague, Dept Biochem & Microbiol, Tech 5, Prague 16628, Czech Republic; [Sykora, David] Univ Chem & Technol Prague, Dept Analyt Chem, Tech 5, Prague 16628, Czech Republic; [Tan, Maria Carmen] De La Salle Univ, Dept Chem, 2401 Taft Ave, Manila 1004, Philippines; [Linis, Virgilio] De La Salle Univ, Dept Biol, 2401 Taft Ave, Manila 1004, Philippines; [Oyong, Glenn] De La Salle Univ, Mol Sci Unit Lab, Ctr Nat Sci & Environm Res, 2401 Taft Ave, Manila 1004, Philippines in 2021.0, Cited 66.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4

Selaginella P. Beauv. is a group of vascular plants in the family Selaginellaceae Willk., found worldwide and numbering more than 700 species, with some used as foods and medicines. The aim of this paper was to compare methanolic (MeOH) and dichloromethane (DCM) extracts of eight Selaginella species on the basis of their composition and biological activities. Six of these Selaginella species are underinvestigated. Using ultra-high performance liquid chromatography-high-resolution mass spectrometry (UHPLC-HRMS) analysis, we identified a total of 193 compounds among the tested Selaginella species, with flavonoids predominating. MeOH extracts recovered more constituents that were detected, including selaginellins, the occurrence of which is only typical for this plant genus. Of all the tested species, Selaginella apoda contained the highest number of identified selaginellins. The majority of the compounds were identified in S. apoda, the fewest compounds in Selaginella cupressina. All the tested species demonstrated antioxidant activity using oxygen radical absorption capacity (ORAC) assay, which showed that MeOH extracts had higher antioxidant capacity, with the half maximal effective concentration (EC50) ranging from 12 +/- 1 (Selaginella myosuroides) to 124 +/- 2 (Selaginella cupressina) mg/L. The antioxidant capacity was presumed to be correlated with the content of flavonoids, (neo)lignans, and selaginellins. Inhibition of acetylcholinesterase (AChE) was mostly discerned in DCM extracts and was only exhibited in S. myosuroides, S. cupressina, Selaginella biformis, and S. apoda extracts with the half maximal inhibitory concentration (IC50) in the range of 19 +/- 3 to 62 +/- 1 mg/L. Substantial cytotoxicity against cancer cell lines was demonstrated by the MeOH extract of S. apoda, where the ratio of the IC50 HEK (human embryonic kidney) to IC50 HepG2 (hepatocellular carcinoma) was 7.9 +/- 0.2. MeOH extracts inhibited the production of nitrate oxide and cytokines in a dose-dependent manner. Notably, S. biformis halved the production of NO, tumor necrosis factor (TNF)-alpha, and interleukin (IL)-6 at the following concentrations: 105 +/- 9, 11 +/- 1, and 10 +/- 1 mg/L, respectively. Our data confirmed that extracts from Selaginella species exhibited cytotoxicity against cancer cell lines and AChE inhibition. The activity observed in S. apoda was the most promising and is worth further exploration.

Application In Synthesis of Methyl 3-phenyl-2-propenoate. Bye, fridends, I hope you can learn more about C10H10O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics