Month: October 2021

An article Carboxylation of Aryl Triflates with CO2 Merging Palladium and Visible-Light-Photoredox Catalysts WOS:000473116000050 published article about C-H FUNCTIONALIZATION; CARBON-DIOXIDE; DUAL CATALYSIS; DRIVEN CARBOXYLATION; UNACTIVATED PRIMARY; BUILDING-BLOCK; BONDS; HALIDES; ACIDS; HYDROCARBOXYLATION in [Bhunia, Samir Kumar; Das, Pritha; Nandi, Shantanu; Jana, Ranjan] CSIR Indian Inst Chem Biol, Organ & Med Chem Div, 4 Raja SC Mullick Rd, Kolkata 700032, W Bengal, India; [Bhunia, Samir Kumar; Jana, Ranjan] Acad Sci & Innovat Res AcSIR, Kolkata 700032, W Bengal, India in 2019.0, Cited 88.0. Safety of 6H-Benzo[c]chromen-6-one. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9

We report herein a visible-light-promoted, highly practical carboxylation of readily accessible aryl triflates at ambient temperature and a balloon pressure of CO2 by the combined use of palladium and photoredox Ir(III) catalysts. Strikingly, the stoichiometric metallic reductant is replaced by a nonmetallic amine reductant providing an environmentally benign carboxylation process. In addition, one-pot synthesis of a carboxylic acid directly from phenol and modification of estrone and concise synthesis of pharmaceutical drugs adapalene and bexarotene have been accomplished via late-stage carboxylation reaction. Furthermore, a parallel decarboxylation-carboxylation reaction has been demonstrated in an H-type closed vessel that is an interesting concept for the strategic sector. Spectroscopic and spectroelectrochemical studies indicated electron transfer from the Ir(III)/DIPEA combination to generate aryl carboxylate and Pd(0) for catalytic turnover.

Safety of 6H-Benzo[c]chromen-6-one. About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Bhunia, SK; Das, P; Nandi, S; Jana, R or concate me.

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Baker, MA; Demoret, RM; Ohtawa, M; Shenvi, RA in [Baker, Meghan A.; Demoret, Robert M.; Ohtawa, Masaki; Shenvi, Ryan A.] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA; [Ohtawa, Masaki] Kitasato Univ, Grad Sch Pharmaceut Sci, Tokyo, Japan published Concise asymmetric synthesis of (-)-bilobalide in 2019, Cited 29. Quality Control of Methyl 2,2-dimethoxyacetate. The Name is Methyl 2,2-dimethoxyacetate. Through research, I have a further understanding and discovery of 89-91-8.

The Ginkgo biloba metabolite bilobalide is widely ingested by humans but its effect on the mammalian central nervous system is not fully understood(1-4). Antagonism of gamma-aminobutyric acid A receptors (GABA(A)Rs) by bilobalide has been linked to the rescue of cognitive deficits in mouse models of Down syndrome(5). A lack of convulsant activity coupled with neuroprotective effects have led some to postulate an alternative, unidentified target(4); however, steric congestion and the instability of bilobalide(1,2,6) have prevented pull-down of biological targets other than the GABA(A)Rs. A concise and flexible synthesis of bilobalide would facilitate the development of probes for the identification of potential new targets, analogues with differential selectivity between insect and human GABA(A)Rs, and stabilized analogues with an enhanced serum half-life(7). Here we exploit the unusual reactivity of bilobalide to enable a late-stage deep oxidation that symmetrizes the molecular core and enables oxidation states to be embedded in the starting materials. The same overall strategy may be applicable to G. biloba congeners, including the ginkgolides-some of which are glycine-receptor-selective antagonists(8). A chemical synthesis of bilobalide should facilitate the investigation of its biological effects and its therapeutic potential.

Quality Control of Methyl 2,2-dimethoxyacetate. About Methyl 2,2-dimethoxyacetate, If you have any questions, you can contact Baker, MA; Demoret, RM; Ohtawa, M; Shenvi, RA or concate me.

Reference:
Patent; U C B, Societe Anonyme; US4041077; (1977); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Authors Pan, C; Wang, LM; Han, JW in AMER CHEMICAL SOC published article about C-F BOND; H DUAL ACTIVATION; CASCADE ANNULATION; CARBOXYLIC-ACIDS; ARYL MIGRATION; ARYLATION; ACCESS; DERIVATIVES; EXTENSION; NITRILES in [Pan, Cheng; Wang, Limin; Han, Jianwei] East China Univ Sci & Technol, Key Lab Adv Mat, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China; [Pan, Cheng; Wang, Limin; Han, Jianwei] East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China; [Han, Jianwei] Chinese Acad Sci, Shanghai Hong Kong Joint Lab Chem Synth, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China in 2020.0, Cited 68.0. Application In Synthesis of 6H-Benzo[c]chromen-6-one. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9

By using 2-fluoro-substituted diaryliodonium salts, a novel benzocylization has been accomplished for the synthesis of 3,4-benzocoumarin derivatives via a cascade of ortho-arylation and defluorination in the presence of palladium catalysts. The reaction exhibits a broad compatibility of readily available aromatic acids with an excellent level of site-selectivity. Mechanistic investigations revealed a unique reactivity of carboxylic acid directed arylation by followed nucleophilic substitution of aromatic fluoride in the present system.

Application In Synthesis of 6H-Benzo[c]chromen-6-one. About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Pan, C; Wang, LM; Han, JW or concate me.

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Formula: C10H12O2. In 2019.0 ORG LETT published article about CATALYZED CARBONYLATIVE SYNTHESIS; BENZYLIC AMINES; CROSS-COUPLINGS; ALKYL IODIDES; FUNCTIONALIZATION; TRANSFORMATIONS; HETEROCYCLES; RADICALS; ALCOHOLS in [Li, Chong-Liang; Wu, Xiao-Feng] Zhejiang Sci Tech Univ, Dept Chem, Xiasha Campus, Hangzhou 310018, Peoples R China; [Li, Chong-Liang; Wu, Xiao-Feng] Univ Rostock, Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany; [Jiang, Xuan; Lu, Liang-Qiu; Xiao, Wen-Jing] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China in 2019.0, Cited 51.0. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3.

The first cobalt-catalyzed deaminative alkoxycarbonylation reaction was described for the conversion of readily available primary alkyl amines to synthetically versatile esters with moderate to high yields. This transformation shows good functional group compatibility and can serve as a powerful tool for the modification of alkyl amine-containing complex natural products and drug molecules.

About Methyl 3-phenylpropionate, If you have any questions, you can contact Li, CL; Jiang, X; Lu, LQ; Xiao, WJ; Wu, XF or concate me.. Formula: C10H12O2

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: 2005-10-9. Recently I am researching about C-H AMINATION; EXCITED-STATE; LIGNIN; BENZENE; SPIROCYCLIZATION; NAPHTHALENE; DERIVATIVES; CYCLIZATION; OXIDATION; CLEAVAGE, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21711530020, 21721004, 21690082, 21690084, 21690080]; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDB17020300, XDB17000000]; STINT [CH2016-6755]; NSFCNational Natural Science Foundation of China (NSFC); Swedish Energy AgencySwedish Energy Agency [P39427-1]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Li, HJ; Subbotina, E; Bunrit, A; Wang, F; Samec, JSM. The CAS is 2005-10-9. Through research, I have a further understanding and discovery of 6H-Benzo[c]chromen-6-one

The idea of using biaryl structures to generate synthetic building blocks such as spirolactones is attractive because biaryl structures are abundant in biomass waste streams. However, the inertness of aromatic rings of biaryls makes it challenging to transform them into functionalized structures. In this work, we developed photoinduced dearomatization of nonphenolic biaryl compounds to generate spirolactones. We demonstrate that dearomatization can be performed via either aerobic photocatalysis or anaerobic photooxidation to tolerate specific synthetic conditions. In both pathways, dearomatization is induced by electrophilic attack of the carboxyl radical. The resulting spirodiene radical is captured by either oxygen or water in aerobic and anaerobic systems, respectively, to generate the spirodienone. These methods represent novel routes to synthesize spirolactones from the biaryl motif.

Recommanded Product: 2005-10-9. About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Li, HJ; Subbotina, E; Bunrit, A; Wang, F; Samec, JSM or concate me.

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Facile synthesis of a highly efficient Co/Cu@NC catalyst for base-free oxidation of alcohols to esters WOS:000536157700015 published article about SELECTIVE TRANSFER HYDROGENATION; ACTIVE-SITES; NANOPARTICLES; ESTERIFICATION; CO; ALDEHYDES; FE; NITROARENES; PERFORMANCE; COMPLEXES in [Jiang, Jiusheng; Li, Xiang; Du, Shengyu; Shi, Langchen; Jiang, Pingping; Zhang, Pingbo; Dong, Yuming; Leng, Yan] Jiangnan Univ, Sch Chem & Mat Engn, Lihu Rd 1800, Wuxi 214122, Jiangsu, Peoples R China in 2020.0, Cited 48.0. Safety of Methyl 3-phenyl-2-propenoate. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4

The direct oxidation of alcohols to esters is an environmentally benign and cost-effective organic synthetic strategy, but it is still a great challenge to discover an economic, highly active, and long-term stable catalyst for efficient transformation of alcohols to esters under milder conditions. Herein, we developed cobalt and copper nanoparticle -co-decorated nitrogen-doped carbon catalysts (CoCu@NCn) through two steps of ball milling and calcination. It was found that CoCu@NCn could catalyze the oxidation of alcohols to esters effectively in the absence of basic additives. The catalytic activity was much higher than those of monometallic Co@NC2 and Cu@NC2 samples, and the catalyst can be conveniently recovered and quite steadily reused. Through a series of control experiments and characterizations, it is concluded that the remarkable catalytic performance of CoCu@NC2 was associated with the synergistic effect between the two metal components, the enhanced basic active sites and the active surface area.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Jiang, JS; Li, X; Du, SY; Shi, LC; Jiang, PP; Zhang, PB; Dong, YM; Leng, Y or concate me.. Safety of Methyl 3-phenyl-2-propenoate

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: 2005-10-9. Recently I am researching about TRANSITION-METAL-COMPLEXES; KETONE ALPHA-ALKYLATION; ASYMMETRIC HYDROGENATION; BORONIC ESTERS; SIMPLE OLEFINS; VINYL ETHERS; RHODIUM; HYDROARYLATION; DIPHOSPHINES; HYDROFORMYLATION, Saw an article supported by the University of ChicagoUniversity of Chicago; NSFNational Science Foundation (NSF) [CHE-1855556]; Dalian Institute of Chemical Physics international talent training project. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Chen, XY; Zhou, XK; Wang, JC; Dong, GB. The CAS is 2005-10-9. Through research, I have a further understanding and discovery of 6H-Benzo[c]chromen-6-one

In contrast to the plethora of large-bite-angle bisphosphine ligands available to transition-metal catalysis, the development of small-bite-angle bisphosphine ligands has suffered from the limited structural variations accessible on their single-atom-containing backbones. Herein, we report the design and applications of a discrete very small bite-angle bisphosphine ligand, namely, FMPhos. Featuring a fluorene-methylene unit appended on the single-carbon linker, the ligand harbors an unusually rigid backbone that presumably stabilizes its complexation with transition metals during catalysis. Compared with the known dppm ligand, it exhibited superior reactivity and regioselectivity in a number of alkene hydrofunctionalization reactions, catalyzed by iridium and rhodium.

Recommanded Product: 2005-10-9. About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Chen, XY; Zhou, XK; Wang, JC; Dong, GB or concate me.

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2020.0 CATALYSTS published article about CHEMOSELECTIVE HYDROGENATION; ALPHA,BETA-UNSATURATED SULFONES; DIHYDROCHALCONES; PALLADIUM; KETONES; RASPBERRY; ALCOHOLS; GINGER; OXIDE in [Cavuoto, Denise] Univ Milan, Dept Chem, Via Golgi 19, I-20133 Milan, Italy; [Cavuoto, Denise; Zaccheria, Federica; Ravasio, Nicoletta] CNR SCITEC, Via C Golgi 19, I-20133 Milan, Italy; [Marelli, Marcello] CNR SCITEC, Via G Fantoli 16-15, I-20138 Milan, Italy; [Evangelisti, Claudio] CNR ICCOM, Via G Moruzzi 1, I-56124 Pisa, Italy; [Piccolo, Oreste] SCSOP, Via Borno 5, I-23896 Sirtori, LC, Italy in 2020.0, Cited 41.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Recommanded Product: Methyl 3-phenyl-2-propenoate

The substitution of complex hydrides and Ni- and noble metal-based catalysts in the synthesis of pharma and fragrance products is a relevant topic in the green chemistry scenario. Here, we report that non-toxic, non-noble metal-based Cu/SiO(2)catalysts are effective and very selective in the hydrogenation of alpha,beta-unsaturated ketones, esters and sulfones under very mild conditions. Vanillyl acetone can be obtained in quantitative yield in 1 h at 90 degrees C and 1 bar of H-2. High dispersion of the metallic phase and support wettability play a significant role in determining catalytic performance.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Cavuoto, D; Zaccheria, F; Marelli, M; Evangelisti, C; Piccolo, O; Ravasio, N or concate me.. Recommanded Product: Methyl 3-phenyl-2-propenoate

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, JF; Sekiguchi, Y; Yoshikai, N in [Yang, Junfeng; Sekiguchi, Yoshiya; Yoshikai, Naohiko] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore; [Yang, Junfeng] Fudan Univ, Dept Chem, 2005 Songhu Rd, Shanghai 2000438, Peoples R China published Cobalt-Catalyzed Enantioselective and Chemodivergent Addition of Cyclopropanols to Oxabicyclic Alkenes in 2019.0, Cited 71.0. Category: esters-buliding-blocks. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3.

We report herein cobalt-catalyzed enantioselective and chemodivergent reactions between a cyclopropanol and an oxabicyclic alkene via a cobalt homoenolate, which afford either an alkylative ring-opening product or a hydroalkylation product, with the counterion of the cobalt catalyst being a major chemoselectivity-controlling factor. A catalyst generated from cobalt(II) chloride and a chiral diphosphine promotes alkylative ring opening to afford 1,2-dihydronaphthalen-1-ol derivatives in good yields with high enantioselectivity. By contrast, a catalyst generated from cobalt(II) acetate and the same diphosphine ligand, with the assistance of methanol, selectively affords hydroalkylation products with retention of the bicyclic structure at a comparable level of enantioselectivity.

Category: esters-buliding-blocks. About Methyl 3-phenylpropionate, If you have any questions, you can contact Yang, JF; Sekiguchi, Y; Yoshikai, N or concate me.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Khosravi, K; Naserifar, S in [Khosravi, Kaveh; Naserifar, Shirin] Arak Univ, Dept Chem, Fac Sci, Arak 3815688349, Iran published Urea-2,2-dihydroperoxypropane as a Novel and High Oxygen Content Alternative to Dihydroperoxypropane in Several Oxidation Reactions in 2019.0, Cited 61.0. Category: esters-buliding-blocks. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9.

Urea-2,2-dihydroperoxypropane (UDHPP)- a white crystalline solid oxidant which is formed when urea is recrystallized from dihydroperoxypropane- was applied as the terminal oxidant in several oxidative procedures namely epoxidation of alpha, beta-unsaturated ketones and alkenes, oxidation of sulfides to sulfoxides and sulfones, bayer-villeger reaction, bromination and iodation of aniline and phenol derivatives, oxidative esterification, oxidative amidation of aromatic aldehydes, thiocyanation of aromatic compounds, and oxidation of pyridines, oxidation of secondary, allylic and benzylic alcohols. All the approaches were carried out under mild conditions and short reaction times and afforded the corresponding products in high yields.

Category: esters-buliding-blocks. About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Khosravi, K; Naserifar, S or concate me.

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics