Month: October 2021

In 2020.0 NUTRIENTS published article about KNEE OSTEOARTHRITIS; NITRIC-OXIDE; MATRIX METALLOPROTEINASES; ARTICULAR CHONDROCYTES; RHEUMATOID-ARTHRITIS; SUPEROXIDE-DISMUTASE; HYDROGEN-PEROXIDE; SYNOVIAL-FLUID; EXPRESSION; MANAGEMENT in [Micheli, Laura; Di Cesare Mannelli, Lorenzo; Cinci, Lorenzo; D’Ambrosio, Mario; Luceri, Cristina; Ghelardini, Carla] Univ Florence, Dept Neurosci Psychol Drug Res & Child Hlth NEURO, Pharmacol & Toxicol Sect, Viale Gaetano Pieraccini 6, I-50139 Florence, Italy; [Mattoli, Luisa; Tamimi, Sara; Flamini, Enrico; Garetto, Stefano; Lucci, Jacopo; Giovagnoni, Emiliano] Aboca SpA Soc Agr, Innovat & Med Sci Div, Loc Aboca 20, I-52037 Sansepolcro, Italy; [Garetto, Stefano; Lucci, Jacopo] Nat Biomed SpA, Loc Aboca 20, I-52037 Sansepolcro, Italy in 2020.0, Cited 74.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Recommanded Product: 103-26-4

Current pharmacological therapies for the management of chronic articular diseases are far from being satisfactory, so new strategies need to be investigated. We tested the intra-articular pain relieving properties of a system of molecules from a characterizedCentella asiaticaextract (14G1862) in a rat model of osteoarthritis induced by monoiodoacetate (MIA). 14G1862 (0.2-2 mg mL(-1)) was intra-articularly (i.a.) injected 7 days after MIA, behavioural and histological evaluations were performed 14, 30 and 60 days after treatments. Moreover, the effect of 14G1862 on nitrate production and iNOS expression in RAW 264.7 macrophages stimulated with LPS was assessed. In vitro, 14G1862 treatment attenuated LPS-induced NO production and iNOS expression in a comparable manner to celecoxib. In vivo, 14G1862 significantly reduced mechanical allodynia and hyperalgesia, spontaneous pain and motor alterations starting on day 14 up to day 60. The efficacy was higher or comparable to that evoked by triamcinolone acetonide (100 mu g i.a.) used as reference drug. Histological evaluation highlighted the improvement of several morphological parameters in MIA + 14G1862-treated animals with particularly benefic effects on joint space and fibrin deposition. In conclusion, i.a. treatment withCentella asiaticais a candidate to be a novel effective approach for osteoarthritis therapy.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Micheli, L; Mannelli, LD; Mattoli, L; Tamimi, S; Flamini, E; Garetto, S; Lucci, J; Giovagnoni, E; Cinci, L; D’Ambrosio, M; Luceri, C; Ghelardini, C or concate me.. Recommanded Product: 103-26-4

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recently I am researching about CARBON-CARBON BONDS; ARYL KETONES; ACTIVATION; EXCHANGE, Saw an article supported by the Education Department of Shaanxi Provincial Government [2018JM2012]; Shaanxi Provincial Education Department [17JS129, 17JK0773]; Key Science and Technology Innovation Team of Shaanxi Province [2017KCT-37]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Jiang, C; Wu, WQ; Lu, H; Yu, TY; Xu, WH; Wei, H. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate. SDS of cas: 103-25-3

A Rh-III-catalyzed Hiyama cross-coupling reaction has been successfully developed. Cleavage of the less polar C-C bond provides an efficient strategy to enable ketones to be as electrophilic reagents, and the corresponding substituted indoles with diverse functional groups are efficiently synthesized in good to high yields.

SDS of cas: 103-25-3. About Methyl 3-phenylpropionate, If you have any questions, you can contact Jiang, C; Wu, WQ; Lu, H; Yu, TY; Xu, WH; Wei, H or concate me.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article 3D printable robust shape memory PET copolyesters with fire safety via pi-stacking and synergistic crosslinking WOS:000476599900044 published article about FLAME-RETARDANT; EPOXY; NETWORKS; THERMO; POLYURETHANE; DEGRADATION; PYROLYSIS; MALEIMIDE; MECHANISM; STRATEGY in [Chen, Lin; Zhao, Hai-Bo; Ni, Yan-Peng; Fu, Teng; Wu, Wan-Shou; Wang, Xiu-Li; Wang, Yu-Zhong] Sichuan Univ, Natl Engn Lab Ecofriendly Polymer Mat Sichuan, Collaborat Innovat Ctr Ecofriendly & Fire Safety, State Key Lab Polymer Mat Engn,Coll Light Ind Tex, Chengdu 610064, Sichuan, Peoples R China in 2019, Cited 49. Quality Control of Dimethyl 5-aminoisophthalate. The Name is Dimethyl 5-aminoisophthalate. Through research, I have a further understanding and discovery of 99-27-4

The practical problems of insufficient mechanical strength, poor processability, tedious synthesis and flammability facing shape memory polymers have limited their further usage in industrial fields, especially in construction and aerospace. A novel and very simple method of ternary polymerization is presented here to prepare multi-functional copolyesters from general poly(ethylene terephthalate) (PET) through the new well-designed third monomer that features pendent phenylacetylene-phenylimide units. The pi-pi stacking between phenylacetylene groups as a reversible net-point not only endows the copolyesters with good shape memory and self-healability, but also reinforces the interchain interaction, leading to high tensile strength (79.6-89.6 MPa). Interestingly enough, the phenylacetylene can synergistically crosslink with the unsaturated C N group generated from the phenylimide during burning, resulting in excellent flame retardancy. Thermoplastic smart copolyesters can be designed into fire alarms and can also be used for 3D printing. The printed geometries exhibit good shape memory behaviors, which could be deformed into a small size to save space during transportation/storage and allow manufacturing freedom for space applications.

Quality Control of Dimethyl 5-aminoisophthalate. About Dimethyl 5-aminoisophthalate, If you have any questions, you can contact Chen, L; Zhao, HB; Ni, YP; Fu, T; Wu, WS; Wang, XL; Wang, YZ or concate me.

Reference:
Patent; ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC.; WO2004/14881; (2004); A2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recently I am researching about O BOND FORMATION; CARBOXYLIC-ACIDS; BENZOCOUMARINS; LACTONIZATION; CYCLIZATION; ACCESS; NIS, Saw an article supported by the JSPS KAKENHIMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) [JP18K05118]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Nakamura, M; Togo, H. The CAS is 2005-10-9. Through research, I have a further understanding and discovery of 6H-Benzo[c]chromen-6-one. Safety of 6H-Benzo[c]chromen-6-one

Treatment of 2-arylbenzoic acids with N-chlorosuccinimide (NCS) and NaI at 70 degrees C under fluorescent lighting condition gave the corresponding 3,4-benzocoumarins in good yields under transition-metal-free condition. It was found that the reactivity of NCS with NaI for the formation of 3,4-benzocoumarins from 2-arylbenzoic acids was as high as that with NIS. Thus, the formation of carboxyl radicals and their cyclization onto an aromatic ring from 2-arylbenzoic acids with much less expensive NCS and NaI, than NIS could be successfully carried out to form 3,4-benzocoumarins.

About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Nakamura, M; Togo, H or concate me.. Safety of 6H-Benzo[c]chromen-6-one

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recently I am researching about BIOMASS PYROLYSIS; MECHANISTIC MODEL; CORN STALK; HEMICELLULOSE; CELLULOSE; LIGNIN; POLYSACCHARIDES; COMPONENTS; BEHAVIORS; PRODUCTS, Saw an article supported by the Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31670582]; National Research and Development Program of China [2017YFB0307901]; Science and Technology Project of Guangzhou City [201607020025]. Published in ELSEVIER SCIENCE BV in AMSTERDAM ,Authors: Liang, JJ; Chen, J; Wu, SB; Liu, C; Lei, M. The CAS is 89-91-8. Through research, I have a further understanding and discovery of Methyl 2,2-dimethoxyacetate. Category: esters-buliding-blocks

Comprehension in hemicellulose pyrolysis is critical to generate renewable fuel and valuable chemical. Herein, a self-designed tubular reactor was applied to observe the appearance alteration and chemical structure evolution during the whole xylan pyrolysis process. Before 200 degrees C, it was free moisture removal stage without significant chemical structure alteration. Xylan began to depolymerize at 200 degrees C corresponding with the appearance change from its original state to dark brown, cleavage of branched-chain and primary product acids & ketones generation. The main chain of xylan was completely broken at 250-350 degrees C via beta-1,4-glycosidic bond cleavage, dehydration, decarboxylation, and decarbonylation reaction. Acids were mainly originated from hemicellulose pyrolysis. The typical signals from FTIR,C-13 CP/MAS NMR were disappeared at 350 degrees C. In the carbonation stage, the C/H and C/O ratio reached 2.01 and 4.54, leading to the aromaticity enhancement of char and formation of carbon-centered radicals.

About Methyl 2,2-dimethoxyacetate, If you have any questions, you can contact Liang, JJ; Chen, J; Wu, SB; Liu, C; Lei, M or concate me.. Category: esters-buliding-blocks

Reference:
Patent; U C B, Societe Anonyme; US4041077; (1977); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Authors Rumyantsev, AV; Pichugov, AV; Bushkov, NS; Aleshin, DY; Strelkova, TV; Lependina, OL; Zhizhko, PA; Zarubin, DN in ROYAL SOC CHEMISTRY published article about in [Rumyantsev, Andrey, V; Pichugov, Andrey, V; Bushkov, Nikolai S.; Aleshin, Dmitry Yu; Strelkova, Tatyana, V; Lependina, Olga L.; Zhizhko, Pavel A.; Zarubin, Dmitry N.] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Vavilov Str 28, Moscow 119991, Russia; [Rumyantsev, Andrey, V; Bushkov, Nikolai S.] Moscow MV Lomonosov State Univ, Dept Chem, Vorobevy Gory 1, Moscow 119991, Russia; [Pichugov, Andrey, V; Aleshin, Dmitry Yu] D Mendeleev Univ Chem Technol Russia, Higher Chem Coll, Miusskaya Sq 9, Moscow 125047, Russia in 2021.0, Cited 33.0. HPLC of Formula: C13H8O2. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9

We report the first examples of direct imidation of lactones giving the corresponding cyclic imidates via oxo/imido heterometathesis with N-sulfinylamines catalysed by a well-defined silica-supported Ti imido complex.

HPLC of Formula: C13H8O2. About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Rumyantsev, AV; Pichugov, AV; Bushkov, NS; Aleshin, DY; Strelkova, TV; Lependina, OL; Zhizhko, PA; Zarubin, DN or concate me.

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Authors Xu, P; Lopez-Rojas, P; Ritter, T in AMER CHEMICAL SOC published article about in [Xu, Peng; Lopez-Rojas, Priscila; Ritter, Tobias] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany in 2021.0, Cited 49.0. Computed Properties of C13H8O2. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9

Abundant aromatic carboxylic acids exist in great structural diversity from nature and synthesis. To date, the synthetically valuable decarboxylative functionalization of benzoic acids is realized mainly by transition-metal-catalyzed decarboxylative cross couplings. However, the high activation barrier for thermal decarboxylative carbometalation that often requires 140 degrees C reaction temperature limits both the substrate scope as well as the scope of suitable reactions that can sustain such conditions. Numerous reactions, for example, decarboxylative fluorination that is well developed for aliphatic carboxylic acids, are out of reach for the aromatic counterparts with current reaction chemistry. Here, we report a conceptually different approach through a low-barrier photoinduced ligand to metal charge transfer (LMCT)-enabled radical decarboxylative carbometalation strategy, which generates a putative high-valent arylcopper(III) complex, from which versatile facile reductive eliminations can occur. We demonstrate the suitability of our new approach to address previously unrealized general decarboxylative fluorination of benzoic acids.

Computed Properties of C13H8O2. About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Xu, P; Lopez-Rojas, P; Ritter, T or concate me.

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Phytochemical variability of selected basil genotypes WOS:000587922300026 published article about ANTIOXIDANT PROPERTIES; ESSENTIAL OIL; 3 CULTIVARS; L.; BIOSYNTHESIS; PHENYLPROPENES; STORAGE in [Zeljkovic, Sanja Cavar; Smekalova, Katerina; Tarkowski, Petr] Crop Res Inst, Ctr Reg Hana Biotechnol & Agr Res, Dept Genet Resources Vegetables Med & Special Pla, Slechtitelu 29, Olomouc 78371, Czech Republic; [Zeljkovic, Sanja Cavar; Komzakova, Karolina; Siskova, Jana; Tarkowski, Petr] Palacky Univ, Ctr Reg Hana Biotechnol & Agr Res, Dept Phytochem, Slechtitelu 27, Olomouc 78371, Czech Republic; [Karalija, Erna] Univ Sarajevo, Fac Sci, Dept Biol, Zmaja Od Bosne 33-35, Sarajevo 71000, Bosnia & Herceg in 2020.0, Cited 45.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. COA of Formula: C10H10O2

Basil (Ocimum basilicum L.), as an aromatic and medicinal plant, exhibits numerous of genotypes that have various applications in food and pharmaceutical industries. Thus, chemical composition is an important parameter for assessing the quality of basil. Hence, twelve European basil genotypes were cultivated under the same conditions, and isolated essential oils and methanol extracts were subjected to detailed chemical analyses and testing their biological activities. According to the analysis of the volatiles, all genotypes belong to linalool chemotype, and they were clustered into two groups. Rosmarinic acid was found to be the major phenylpropanoid, following with luteoin, kaempherol, and rutin. Principal component analysis of phenolic compounds indicated segregation of genotypes in two distinct groups. Biological activities of the isolated extracts were correlated with the concentrations of the actives, and it was found that naringenin, luteolin, and kaempherol are the main carriers of antioxidant activity, while the levels of linalool correlated with tyrosinase inhibition activity. Adversely, methyl chavicol showed negative correlations with both assays. Finally, it was found that Czech genotypes (Litra and Chladek), as well as Dutch (Bush) and Italian (Fino Verde Compatto) possess significant amounts of terpenoid linalool, together with flavonoids luteolin, naringenin, and kaempherol, and therefore, have strong biological activities required for their use in food and cosmetic industries.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Zeljkovic, SC; Komzakova, K; Siskova, J; Karalija, E; Smekalova, K; Tarkowski, P or concate me.. COA of Formula: C10H10O2

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recently I am researching about ACID; CATALYSIS; MOFS, Saw an article supported by the Foundation for Science and Technology (FCT), PortugalPortuguese Foundation for Science and Technology [UID/QUI/00100/2019]; Instituto Superior Tecnico; FCTPortuguese Foundation for Science and TechnologyEuropean Commission [IST-ID/107/2018, IST-ID/197/2019, 57/2016]. Category: esters-buliding-blocks. Published in FRONTIERS MEDIA SA in LAUSANNE ,Authors: Karmakar, A; Paul, A; Rubio, GMDM; Soliman, MMA; Fatima, M; da Silva, CG; Pombeiro, AJL. The CAS is 99-27-4. Through research, I have a further understanding and discovery of Dimethyl 5-aminoisophthalate

A pyridine-based amide functionalized tetracarboxylic acid, 5,5 ‘-(pyridine-2, 6-dicarbonyl)bis(azanediyl)}diisophthalic acid (H4L), was synthesized and its coordination chemistry toward zinc(II) and cadmium(II) ions was studied. The reactions of H4L with Zn(NO3)(2).6H(2)O and Cd(NO3)(2).4H(2)O led to its full or partial deprotonation, respectively, and the formation of the 2D coordination polymers [Zn-2(L)(H2O)(4)](n).4n(H2O) (1) and [Cd-3(HL)(2)(DMF)(4)](n).4n(DMF) (2) (DMF = N,N’-dimethylformamide), respectively. They were characterized by elemental analysis, FT-IR, photoluminescence, thermogravimetry, and single-crystal and powder X-ray diffraction. In 1, the L4- ligand is planar with every carboxylate anion binding a Zn(II) cation and giving rise to a 2D grid with the metals with tetrahedral environments. In 2, the combination of bridging HL3- and dimethylformamide to form trinuclear Cd(II) clusters engenders secondary building block units and generates a layer-type 2D network with the metals with octahedral and pentagonal bipyramid coordination geometries. The topological analyses of 1 and 2 reveal 2,4-connected and 3,6-connected binodal nets, respectively. On account of the presence of Lewis acid (Zn or Cd centers) as well as basic (uncoordinated pyridine and amide groups) sites, 1 and (to a much lower extent) 2 effectively catalyze the one-pot cascade deacetalization-Knoevenagel condensation reactions under quite mild conditions. They act as heterogeneous catalysts, being easy to recover and recycle without losing activity.

About Dimethyl 5-aminoisophthalate, If you have any questions, you can contact Karmakar, A; Paul, A; Rubio, GMDM; Soliman, MMA; Fatima, M; da Silva, CG; Pombeiro, AJL or concate me.. Category: esters-buliding-blocks

Reference:
Patent; ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC.; WO2004/14881; (2004); A2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Comprehensive insights into xylan structure evolution via multi-perspective analysis during slow pyrolysis process WOS:000458225800001 published article about BIOMASS PYROLYSIS; MECHANISTIC MODEL; CORN STALK; HEMICELLULOSE; CELLULOSE; LIGNIN; POLYSACCHARIDES; COMPONENTS; BEHAVIORS; PRODUCTS in [Liang, Jiajin; Chen, Jiao; Wu, Shubin; Liu, Chao; Lei, Ming] South China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Guangdong, Peoples R China in 2019, Cited 42. The Name is Methyl 2,2-dimethoxyacetate. Through research, I have a further understanding and discovery of 89-91-8. Application In Synthesis of Methyl 2,2-dimethoxyacetate

Comprehension in hemicellulose pyrolysis is critical to generate renewable fuel and valuable chemical. Herein, a self-designed tubular reactor was applied to observe the appearance alteration and chemical structure evolution during the whole xylan pyrolysis process. Before 200 degrees C, it was free moisture removal stage without significant chemical structure alteration. Xylan began to depolymerize at 200 degrees C corresponding with the appearance change from its original state to dark brown, cleavage of branched-chain and primary product acids & ketones generation. The main chain of xylan was completely broken at 250-350 degrees C via beta-1,4-glycosidic bond cleavage, dehydration, decarboxylation, and decarbonylation reaction. Acids were mainly originated from hemicellulose pyrolysis. The typical signals from FTIR,C-13 CP/MAS NMR were disappeared at 350 degrees C. In the carbonation stage, the C/H and C/O ratio reached 2.01 and 4.54, leading to the aromaticity enhancement of char and formation of carbon-centered radicals.

About Methyl 2,2-dimethoxyacetate, If you have any questions, you can contact Liang, JJ; Chen, J; Wu, SB; Liu, C; Lei, M or concate me.. Application In Synthesis of Methyl 2,2-dimethoxyacetate

Reference:
Patent; U C B, Societe Anonyme; US4041077; (1977); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics