Recently I am researching about ALPHA,BETA-UNSATURATED 2-ACYL IMIDAZOLES; ASYMMETRIC CONJUGATE ADDITION; MICHAEL ADDITION; DIRECTING GROUPS; H ACTIVATION; CATALYSIS; ACID; COMPLEX; ALKYLATION; ACYLATION, Saw an article supported by the JSPSMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of Science [JP15H05846]; AMED [JP19am0101091]; Takeda Science FoundationTakeda Science Foundation (TSF); Otsuka Toshimi Scholarship FoundationOtsuka Pharmaceutical. Recommanded Product: Methyl 3-phenylpropionate. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Xin, HL; Pang, B; Choi, J; Akkad, W; Morimoto, H; Ohshima, T. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate
2-Acylimidazoles are widely used as post-transformable carboxylic acid equivalents in chemoselective and enantioselective reactions. Their transformations, however, require pretreatment with highly reactive, toxic methylating reagents to facilitate C-C bond cleavage. Here, we demonstrate that such pretreatment can be avoided and the C-C bond cleaved under neutral conditions without the use of additional reagents or catalysts. The scope of the reaction, including the use of products reported in the literature as substrates, and some mechanistic insights are described.
About Methyl 3-phenylpropionate, If you have any questions, you can contact Xin, HL; Pang, B; Choi, J; Akkad, W; Morimoto, H; Ohshima, T or concate me.. Recommanded Product: Methyl 3-phenylpropionate
Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
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