Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , SDS of cas: 924-99-2, 924-99-2, Name is Ethyl 3-(dimethylamino)acrylate, molecular formula is C7H13NO2, belongs to esters-buliding-blocks compound. In a document, author is Pham, Quyen T., introduce the new discover.
Iodine-mediated formal [3+2] annulation for synthesis of furocoumarin from oxime esters
A novel synthesis of furocoumarins was developed by a reaction between oxime esters and 4-hydroxycoumarins. The reaction was proposed to undergo radical mechanism mediated by iodine, a cheap and common laboratory reagent. Mechanistic studies showed the key for the successful transformation was the presence of alpha-iodoimine intermediate which facilitated the ring-closing step. The developed conditions produced good functional group tolerance with a wide range of high-profile furocoumarin product. The potential for this strategy to be applied in other syntheses of heterocyclic compounds is highly achievable.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 924-99-2. SDS of cas: 924-99-2.