83-27-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 83-27-2, name is Diethyl 2-(sec-butyl)malonate, This compound has unique chemical properties. The synthetic route is as follows.
STEP A: 1-(3,4-dichlorophenyl)-4-(sec-butyl)-pyrazolidine-3,5-dione 50 g of 3,4-dichlorophenylhydrazine (85%) and 122.5 g of diethyl sec-butyl-malonate were heated for 10 hours at 180 C. (external temperature) while distilling 21.3 g of ethanol. The remainder was taken up in 200 ml of methylene chloride, and the solution was extracted with 2N sodium hydroxide, then with water. The combined aqueous phases were washed with methylene chloride and acidified to pH 1 by concentrated hydrochloric acid. The precipitate was separated, washed with water, separated, dried under reduced pressure at 40 C. to obtain 64.8 g of 1-(3,4-dichlorophenyl)-4-(sec-butyl)-pyrazolidine-3,5-dione melting at 118-120 C.
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.
Reference:
Patent; Roussel Uclaf; US4808210; (1989); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics